High volume of severe sepsis patients may result in better outcomes

January 17, 2014

A recent study led by Boston University School of Medicine (BUSM) shows that "practice may make perfect" when it comes to caring for patients with severe sepsis. The study showed that patients admitted to academic medical centers that care for more patients with severe sepsis have significantly lower mortality rates than patients cared for at academic medical centers with lower volumes of sepsis patients. Additionally, the superior outcomes at high volume centers were achieved at similar costs compared to the lower volume medical centers.

Published online in the American Journal of Respiratory and Critical Care Medicine, the study was led by Allan J. Walkey, MD, MSc, assistant professor of medicine, BUSM, and attending physician, pulmonary, critical care and allergy medicine, Boston Medical Center.

Analyzing data from academic hospitals across the country, provided by the University HealthSystem Consortium, the researchers identified 56,997 with severe who were admitted to 124 academic hospitals in 2011. The median length of stay for patients was 12.5 days and the median direct cost for each patient was $26,304.

Their data indicate that hospitals caring for more sepsis patients had a seven percent lower mortality rate than hospitals with lower volumes. The high volume medical centers had a 22 percent mortality rate while the lower volume hospitals had a 29 percent mortality rate.

"Given the lack of new drugs to treat severe sepsis, medical professionals must look at other ways to increase patient safety and positive outcomes, including the process of how we deliver care," said Walkey. "Our study results demonstrate that hospitals with more experience caring for patients with were able to achieve better outcomes than hospitals with less experience with sepsis, possibly due to better processes of care for patients with sepsis."

Explore further: Nationwide trends for sepsis in the 21st century

Related Stories

Differences in sepsis care identified in europe, U.S.

October 26, 2012

(HealthDay)—Despite differences in processes of care and raw mortality for patients with severe sepsis and septic shock in the United States and Europe, after adjustment, mortality rates are similar, according to a study ...

Study shows decrease in sepsis mortality rates

November 13, 2013

A recent study from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) shows a significant decrease in severe sepsis mortality rates over the past 20 years. Looking at data from patients with severe ...

Recommended for you

The 'love hormone' may quiet tinnitus

September 23, 2016

(HealthDay)—People suffering from chronic ringing in the ears—called tinnitus—may find some relief by spraying the hormone oxytocin in their nose, a small initial study by Brazilian researchers suggests.

Bile acid uptake inhibitor prevents NASH / fatty liver in mice

September 21, 2016

Drugs that interfere with bile acid recycling can prevent several aspects of NASH (nonalcoholic steatohepatitis) in mice fed a high-fat diet, scientists from Emory University School of Medicine and Children's Healthcare of ...

New therapeutic target for Crohn's disease

September 20, 2016

Research from the Sanford Burnham Prebys Medical Discovery Institute (SBP) identifies a promising new target for future drugs to treat inflammatory bowel disease (IBD). The study, published today in Cell Reports, also indicates ...

Arthritis drug may help with type of hair loss

September 22, 2016

(HealthDay)—For people who suffer from a condition that causes disfiguring hair loss, a drug used for rheumatoid arthritis might regrow their hair, a new, small study suggests.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.