Main intestinal disease bacteria to be sequenced

Main intestinal disease bacteria to be sequenced
Scientists in the Centre for Genomic Research will decode and analyse the 510 archived isolates of Campylobacter from earlier collections of human faeces

The University of Liverpool is to decipher the genomes of the UK's main bacterial cause of food poisoning which results in over 21,000 hospital admissions and 100 deaths each year.

Using the latest whole genome sequencing technologies available at the University's Centre for Genomic Research, scientists will decode and analyse the 510 archived isolates of Campylobacter from earlier collections of human faeces.

Campylobacter

Campylobacter is widely recognised as the main bacterial cause of foodborne infections leading to diarrhoea, and in 2010 was responsible for an estimated 21,300 and 100 deaths in the UK, at a cost of approximately £784 million.

The new project is funded by the Food Standards Agency and, when it concludes in February 2015, scientists will have a greater understanding of sources and transmission routes associated with human Campylobacter. The Agency will then be able to use these results to directly benefit the public health benefits.

The bacterial isolates used in this study were obtained from faecal samples from thousands of people with symptoms of diarrhoea and vomiting during two separate time periods (1993-1996 and 2008-2009).

The research will give scientists key information about the make-up of the UK Campylobacter population and will also link to other research at the University examining Campylobacter found in poultry and the general environment.

Prevention

Professor of microbiology, Craig Winstanley, from the University's Institute of Infection and Global Health is leading the project. He said: "Campylobacter causes misery for thousands of people in the UK every year. The research will give us a much better idea of precisely how the bacteria get into humans and how this might be prevented.

"Working with the Food Standards Agency means that this work can then be turned into concrete public benefits."

add to favorites email to friend print save as pdf

Related Stories

Vaccinating chickens could prevent food-borne illness

Mar 26, 2012

A vaccine could be developed to prevent Campylobacter being carried in chickens. This approach could drastically cut the number of cases of food poisoning, saving the UK economy millions each year, says an American scient ...

Phagevet-P: Applying viruses to treat bacterial diseases

Sep 20, 2012

The quest for enhanced food safety has driven research into novel treatments for bacterial diseases in livestock. A European consortium proposed the use of bacteriophages (bacteria-targeting viruses) to treat ...

Recommended for you

Streets bustling after Sierra Leone shutdown ends

4 hours ago

Streets in Sierra Leone's capital bustled again Monday after an unprecedented nationwide shutdown during which officials said more than 1 million households were checked for Ebola patients and given information ...

Spain: Ebola test drug out of supply worldwide

6 hours ago

Doctors treating a Spanish priest who was repatriated from West Africa on Monday after being diagnosed with the Ebola virus said there were no samples of experimental drug ZMapp available in the world right ...

User comments