Natural plant compounds may assist chemotherapy

March 27, 2014

Researchers at Plant & Food Research have identified plant compounds present in carrots and parsley that may one day support more effective delivery of chemotherapy treatments.

Scientists at Plant & Food Research, working together with at The University of Auckland and the National Cancer Institute of The Netherlands, have discovered specific able to inhibit transport mechanisms in the body that select what compounds are absorbed into the body,and eventually into cells. These same transport mechanisms are known to interfere with cancer chemotherapy treatment.

The teams' research, recently published in the European Journal of Pharmacology, showed that falcarinol type compounds such as those found in carrots and parsley may support the delivery of drug compounds which fight breast cancer by addressing the over-expression of Breast Cancer Resistance Protein (BCRP/ABCG2), a protein that leads to some malignant tissues ability to become resistant to .

"It's very exciting work," says Plant & Food Research Senior Scientist, Dr Arjan Scheepens. "Our work is uncovering new means to alter how the body absorbs specific chemical and natural compounds. Ultimately we are interested in how food could be used to complement conventional treatments to potentially deliver better results for patients."

Explore further: Plant food supplements in the spotlight

Related Stories

Plant food supplements in the spotlight

February 2, 2012

Natural food does not always mean safe food. EU-funded researchers have discovered that the compounds found in some botanicals and botanical preparations, such as plant food supplements, may be detrimental to one's health. ...

Recommended for you

Researchers thwart cancer cells by triggering 'virus alert'

August 27, 2015

Working with human cancer cell lines and mice, researchers at the Johns Hopkins Kimmel Cancer Center and elsewhere have found a way to trigger a type of immune system "virus alert" that may one day boost cancer patients' ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.