Nearly one-third of initial prescriptions remain unfilled

Nearly one-third of initial prescriptions remain unfilled
A sizable number of patients fail to fill their initial drug prescriptions, according to research published in the April 1 issue of the Annals of Internal Medicine.

(HealthDay)—A sizable number of patients fail to fill their initial drug prescriptions, according to research published in the April 1 issue of the Annals of Internal Medicine.

Robyn Tamblyn, Ph.D., of McGill University in Montreal, and colleagues examined data from 15,961 patients in a primary care network to estimate the incidence of primary nonadherence. Primary nonadherence was defined as failure to fill an incident prescription within nine months.

The researchers found that 31.3 percent of 37,506 incident remained unfilled. Prescriptions for drugs in the upper quartile of cost were the least likely to be filled (odds ratio [OR], 1.11; 95 percent confidence interval [CI], 1.07 to 1.17). Compared with anti-infectives, prescriptions for skin agents, gastrointestinal drugs, and autonomic drugs also were less likely to be filled. Prescription nonadherence was less likely with increasing patient age (OR per 10 years, 0.89; 95 percent CI, 0.85 to 0.92), elimination of copayments for in low-income groups (OR, 0.37; 95 percent CI, 0.32 to 0.41), and greater proportion of all physician visits with the prescribing physician (OR per 0.5 increase, 0.77; 95 percent CI, 0.70 to 0.85).

"Primary nonadherence is common and may be reduced by lower drug costs and copayments, as well as increased follow-up care with prescribing physicians for patients with chronic conditions," the authors write.

More information: Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Stage III/IV melanoma patients at risk for new primaries

Dec 10, 2013

(HealthDay)—Patients with stage III or IV melanoma who have not received treatment with BRAF inhibitors remain at risk for developing new primary melanomas (NPMs), although the incidence rates are lower ...

Metformin use doesn't cut incidence of bladder cancer

Feb 11, 2014

(HealthDay)—For patients with type 2 diabetes, metformin use is not associated with a significantly reduced risk of bladder cancer, according to a study published online Feb. 4 in Diabetes Care.

Melanoma risk up in IBD independent of biologic therapy

Jan 31, 2014

(HealthDay)—Inflammatory bowel disease (IBD) is associated with an increased risk of melanoma, independent of the use of biologic therapy, according to research published in the February issue of Clinical Ga ...

Recommended for you

Preterm children's brains can catch up years later

37 minutes ago

There's some good news for parents of preterm babies – latest research from the University of Adelaide shows that by the time they become teenagers, the brains of many preterm children can perform almost as well as those ...

Mortality rates increase due to extreme heat and cold

57 minutes ago

Epidemiological studies have repeatedly shown that death rates rise in association with extremely hot weather. The heat wave in Western Europe in the summer of 2003, for example, resulted in about 22,000 extra deaths. A team ...

It takes more than practice to excel, psychologist reports

1 hour ago

Case Western Reserve University's new assistant professor of psychology Brooke N. Macnamara, PhD, and colleagues have overturned a 20-year-old theory that people who excel in their fields are those who practiced the most.

User comments