Inflammation tied to depressive symptoms in new T2DM

Inflammation tied to depressive symptoms in new T2DM

(HealthDay)—For patients with newly diagnosed type 2 diabetes, inflammatory markers are associated with depressive symptoms, according to a study published online May 19 in Diabetes Care.

Jean-Pierre S. Laake, from King's College London, and colleagues examined the correlation between depressive symptoms in adults and newly diagnosed type 2 diabetes and concentrations of . Depressive symptoms were assessed using the Patient Health Questionnaire-9. Twelve markers of inflammation were measured in 1,790 participants recruited from primary care.

The researchers found that depressive symptoms were associated with C-reactive protein (P < 0.001); interleukin (IL)-1β (P = 0.047); IL-1 receptor antagonist (P < 0.001); monocyte chemotactic protein-1 (P = 0.001); white (P < 0.001); and triglycerides (P < 0.001). These correlations were seen after adjustment for covariates, including sociodemographic factors, adiposity, macrovascular disease, glycated hemoglobin, and prescribed medication.

"Increased inflammation may be involved in the pathogenesis of in type 2 diabetes and contribute to the increased risk of complications and mortality in this group," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Magnesium cuts diabetes risk

Oct 20, 2014

Getting enough magnesium in the diet may reduce the risk of diabetes, especially for those who already show signs of heading that way.

Personalised treatment for stress-related diabetes

Oct 14, 2014

Researchers at Lund University in Sweden are testing a treatment for type 2 diabetes which targets the disease mechanism itself - and not just the symptoms. For the first time, knowledge about the individual patient's genetic ...

User comments