The Broad Institute is a genomic medicine research center located in Cambridge, Massachusetts, United States. Although it is independently governed and supported as a 501(c)(3) nonprofit research organization, the institute is formally affiliated with the Massachusetts Institute of Technology, Harvard University and its affiliated hospitals. The faculty and staff of the Broad Institute include physicians, geneticists, and molecular, chemical, and computational biologists.
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When the body's defense cells detect harmful pathogens they kill them and alert rest of the immune system. Sometimes this killing goes overboard, and our defense system starts attacking healthy cells leading to a condition ...
Jul 25, 2018
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Drugs for diabetes, inflammation, alcoholism—and even for treating arthritis in dogs—can also kill cancer cells in the lab, according to a study by scientists at the Broad Institute of MIT and Harvard and Dana-Farber ...
Jan 20, 2020
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Patients with atrial fibrillation (AF), a condition causing a rapid, irregular heart rate that can increase the risk of stroke, could use some new treatment options. Despite how common the condition is, the current treatment ...
Jun 12, 2018
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The main treatment for bipolar disorder, lithium, was approved a half-century ago but doesn't help all patients and has significant side effects. Little progress has been made in finding better therapies, in part because ...
Apr 7, 2022
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Changes in the gut microbiome have long been linked with Crohn's disease and other forms of inflammatory bowel disease (IBD), but the biology behind those links has remained murky. Researchers at the Broad Institute, Massachusetts ...
Jun 11, 2019
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Centenarians are less susceptible to age-related chronic diseases and more likely to survive infectious diseases. Now, a new study reveals that people who live to be 100 or older have a unique microbiome that may protect ...
Jul 30, 2021
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A landmark study, based on genetic analysis of nearly 65,000 people, has revealed that a person's risk of schizophrenia is increased if they inherit specific variants in a gene related to "synaptic pruning"—the elimination ...
Jan 27, 2016
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Progressive kidney diseases, whether caused by obesity, hypertension, diabetes, or rare genetic mutations, often have the same outcome: The cells responsible for filtering the blood are destroyed. Reporting today in Science, ...
Dec 7, 2017
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Embedded throughout the gastrointestinal system is an extensive array of neurons that coordinates nearly all activities involved in digestion, gut motility, and response to noxious stimuli. These cells make up the enteric ...
Sep 4, 2020
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Although the outlook for people with some types of cancers has improved in the past 20 years, outcomes for patients with uterine and ovarian cancers remain much the same. Patients often have advanced disease before they are ...
Apr 19, 2022
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