Organoids are carefully grown collections of cells in a dish, designed to mimic organ structures and composition better than conventional cell cultures and give researchers a unique view into how organs such as the brain ...
Sep 30, 2022
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Trillions of bacteria and other microbes thrive in our gut microbiomes, and over the last decade, scientists have become increasingly aware of the vital role that they play in creating a healthy gastrointestinal environment. ...
Sep 19, 2022
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The treatment of blood cancers has dramatically improved in the last five years, thanks to a new class of cancer immunotherapies called CAR-T cell therapy. This therapy—which involves engineering a patient's own T cells ...
Sep 13, 2022
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In 2006, researchers discovered that people with certain variants of the gene PCSK9 had dramatically lower cholesterol levels than the general population. Individuals with two broken copies of the gene—one from each parent—were ...
Aug 16, 2022
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Physician-scientists at the Broad Institute of MIT and Harvard and Dana-Farber Cancer Institute have discovered that a gene called FOXR2 that is normally turned off in most tissues in the body is activated in at least 70% ...
Jul 22, 2022
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Some of the most infamous drivers of cancer are mutations in RAS genes, which lead to tumor growth in about a quarter of all cancer patients. Scientists at the Broad Institute of MIT and Harvard and the Dana-Farber Cancer ...
Jul 14, 2022
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Scientists from the Precision Cardiology Lab (PCL) of the Broad Institute of MIT and Harvard and Bayer have generated detailed maps of a variety of cell types in the heart that are involved in two major causes of heart failure: ...
Jun 23, 2022
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118
Scientists at the Broad Institute of MIT and Harvard and the University of Massachusetts Medical School have developed a machine-learning model that can analyze millions of SARS-CoV-2 genomes and predict which viral variants ...
May 25, 2022
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Our genome contains vast networks that regulate the activity of protein-coding genes. Variations in this regulatory DNA (which does not encode proteins) may affect both when and how much of a given protein a cell produces. ...
May 9, 2022
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By introducing cancer-causing mutations into healthy skin cells step-by-step, Broad scientists have created models of skin cancer that can reveal the effects of mutations.
Apr 29, 2022
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