Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is headquartered in Chevy Chase, Maryland. HHMI was founded in 1953 and has flourished as the foremost benefactor for basic research in the areas of molecular biology, genetics, immunology and biomedical research. HHMI has a $17.5 billion dollar endowment and yearly awards around $450 million dollars to scientists in university labs involved in scientific pursuits that coincide with industrialists Howard Hughes' goal of discovering the “genesis of life itself”.
Chevy Chase, MD 20815-6789
Finding a new way to manage infections
(Medical Xpress)—Waging an immunological war against a pathogen is not the body's only way to survive an infection. Sometimes tolerance, or learning to live with an invader, can be just as important. In tolerance the body ...
Immunology
Apr 29, 2013 |
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Scientists make insulin-producing cells self-replicate
(Medical Xpress)—Scientists have discovered a hormone that causes the body's insulin-producing factories, beta cells, to churn out more of themselves. Having enough insulin is critical to regulating the amount of sugar ...
Medical research
Apr 29, 2013 |
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Scientists find mechanism that triggers immune responses to DNA
(Medical Xpress)—Free-floating pieces of DNA in a cell's watery interior can mean bad things: invading viruses, bacteria, or parasites, ruptured cellular membranes, or disease. Genetic material is meant to be contained ...
Medical research
Dec 21, 2012 |
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Search for epigenetic decoder leads scientists to Rett Syndrome
(Medical Xpress)—A few years ago, scientists discovered an unexpected layer of information woven into the genetic code – a nucleotide called 5-hydroxymethylcytosine, or 5hmC. Its meaning was unknown at the time, but a ...
Medical research
Dec 21, 2012 |
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A study in adaptability: Why do we change our beliefs?
(Medical Xpress)—The human brain likes to make predictions about how the world works. Imagine, for example, that you move to a new town. At first, you don't know where to go for dinner. But after weeks of trying different ...
Neuroscience
Oct 09, 2012 |
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Kidney disease linked to defects in cells' ability to repair damaged DNA
(Medical Xpress) -- Howard Hughes Medical Institute investigator Friedhelm Hildebrandt has discovered that genetic mutations that impair cells’ ability to repair damaged DNA can cause chronic kidney disease.
Genetics
Aug 07, 2012 |
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New molecular structure offers first picture of a protein family vital to human health
The 20 proteins in the Wnt family are some of the most important proteins in controlling how an organism develops and grows, but for 30 years scientists have not known what these vital proteins actually look ...
Medical research
May 31, 2012 |
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Researchers identify key brain cell in antidepressant action
(Medical Xpress) -- Antidepressant medications such as Prozac have helped improve mood and lessen anxiety in millions of people with major depression. But scientists know surprisingly little about how these drugs work.
Medical research
May 25, 2012 |
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Positive feedback in the developing brain
(Medical Xpress) -- When an animal is born, its early experiences help map out the still-forming connections in its brain. As neurons in sensory areas of the brain fire in response to sights, smells, and sounds, ...
Neuroscience
May 16, 2012 |
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Century-long protein hunt ends with chance discovery on bone biology
(Medical Xpress) -- In 1883, Swedish chemist Olof Hammarsten discovered that milk proteins called caseins contain not just the known building blocks of proteins, but also the chemical phosphate. It was the first hint that ...
Medical research
May 10, 2012 |
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Epigenetic culprit in Alzheimer's memory decline
In a mouse model of Alzheimer's disease, memory problems stem from an overactive enzyme that shuts off genes related to neuron communication, a new study says.
Medical research
Feb 29, 2012 |
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New drug extends survival in patients with drug-resistant prostate cancer
A new drug, MDV3100, is improving the survival rate in men with advanced prostate cancer, results of a large, phase III clinical trial show. The drug is designed to block a type of cellular receptor that drives progression ...
Cancer
Feb 01, 2012 |
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Exercise triggers beneficial cellular recycling: study
Everyone knows exercise is good for you. We’re told time spent on the treadmill can reduce our risk of diabetes, cancer, and cardiovascular disorders. But exactly how exercise provides this protection ...
Medical research
Jan 18, 2012 |
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Gene hunters find cause of rare movement disorder
(Medical Xpress) -- After a challenging two-decade hunt, scientists have pinpointed the gene responsible for a rare disease that causes seizures in infancy and sudden, uncontrollable movements in adolescence and early adulthood.
Genetics
Dec 16, 2011 |
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Hunger and hormones determine food's appeal
(Medical Xpress) -- It’s been said that there are two kinds of eating: eating to survive, or satisfy hunger, and eating for pleasure. The pathways in the brain that control each urge have been studied independently. ...
Neuroscience
Nov 25, 2011 |
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