Journal of Clinical Investigation

Gene variants may play role in obesity

(HealthDay)—Two new studies offer some solace to those who can't control their weight despite diet and exercise by providing more evidence that genetics may play a role in obesity.

Jun 17, 2013
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Tipping the balance between senescence and proliferation

An arrest in cell proliferation, also referred to as cellular senescence, occurs as a natural result of aging and in response to cellular stress. Senescent cells accumulate with age and are associated with many aging phenotypes, ...

Nov 15, 2013
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Liver tropism is key for B cell deletion immunotherapy

Antibodies against the B cell surface protein CD20 have been used successfully to treat B cell-mediated autoimmune diseases and lymphomas. Antibody binding receptors, called Fc receptors, on other immune cells bind anti-CD20 ...

Nov 01, 2013
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