Massachusetts General Hospital
Study identifies growth factor essential to the most common malignant pediatric brain tumor
A multi-institutional team led by Massachusetts General Hospital (MGH) researchers has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common ...
Cancer
Feb 28, 2013 |
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Extremely high estrogen levels may underlie complications of single-birth IVF pregnancies
Massachusetts General Hospital (MGH) researchers have identified what may be a major factor behind the increased risk of two adverse outcomes in pregnancies conceived through in vitro fertilization (IVF). Two papers published ...
Obstetrics & gynaecology
Feb 25, 2013 |
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Cellular renewal process may underlie benefits of omega fatty acids
A search for genes that change their levels of expression in response to nutrient deprivation has uncovered potential clues to the mechanism underlying the health benefits of omega fatty acids. In the Feb. 15 issue of Genes & ...
Health
Feb 13, 2013 |
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Mouse models fail to reproduce inflammatory genomic response to serious injuries
Existing mouse models do not appear to accurately reproduce the human genomic response to serious traumatic injury, including major burns, according to an article appearing in PNAS Early Edition.
Inflammatory disorders
Feb 11, 2013 |
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Transition in cell type parallels treatment response, disease progression in breast cancer
A process that normally occurs in developing embryos – the changing of one basic cell type into another – has also been suspected of playing a role in cancer metastasis. Now a study from Massachusetts General Hospital ...
Cancer
Jan 31, 2013 |
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Study clarifies antidepressant contribution to arrhythmia risk
A 2011 warning from the U.S. Food and Drug Administration about the popular antidepressant citalopram (Celexa) left many patients and physicians with more questions than answers. Now an analysis of the medical records of ...
Medications
Jan 29, 2013 |
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Neuroinflammation may be behind general-anesthesia-associated learning disabilities
Several studies have found evidence that children who undergo repeated surgical operations with general anesthesia before the age of 4 may be at an increased risk for learning disabilities. In the March issue of Anesthesiology, Massac ...
Diseases, Conditions, Syndromes
Jan 24, 2013 |
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Generic HIV treatment strategy could save nearly $1 billion annually but may be less effective
Replacing the combination of brand-name, antiretroviral drugs currently recommended for control of HIV infection with soon-to-be-available generic medications could save the U.S. health care system almost $1 billion a year ...
HIV & AIDS
Jan 14, 2013 |
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Drug overdose now the leading cause of death among homeless adults in Boston
Drug overdose was the leading cause of death among homeless adults in Boston from 2003 to 2008 and accounted for one-third of deaths among those ages 25 to 44. A study by investigators from Massachusetts General Hospital ...
Health
Jan 14, 2013 |
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Impaired coordination of brain activity in autism involves local, as well as long-range, signaling
A study based at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH) finds that the local functional connectivity of the brain – the extent to which the activity of within a small brain region ...
Autism spectrum disorders
Jan 14, 2013 |
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Pill-sized device provides rapid, detailed imaging of esophageal lining
Physicians may soon have a new way to screen patients for Barrett's esophagus, a precancerous condition usually caused by chronic exposure to stomach acid. Researchers at the Wellman Center for Photomedicine ...
Medical research
Jan 13, 2013 |
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Many physicians often fulfill patient requests for brand-name drugs instead of equivalent generics
More than a third of U.S. physicians responding to a national survey indicated they often or sometimes prescribed brand-name drugs when appropriate generic substitutes were available simply because patients requested the ...
Medications
Jan 07, 2013 |
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Genetic manipulation of urate alters neurodegeneration in mouse model of Parkinson's disease
A study by Massachusetts General Hospital researchers adds further support to the possibility that increasing levels of the antioxidant urate may protect against Parkinson's disease. In their report published in PNAS Early ...
Parkinson's & Movement disorders
Dec 17, 2012 |
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Intestinal immune cells play an unexpected role in immune surveillance of the bloodstream
A type of immune cell found in the small intestine plays a previously unsuspected role in monitoring antigens circulating in the bloodstream. The findings from a team of Massachusetts General Hospital (MGH) researchers clarify ...
Immunology
Dec 13, 2012 |
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Educational video helps terminal cancer patients decide whether to receive CPR
Patients with terminal cancer who viewed a three-minute video demonstrating cardiopulmonary resuscitation (CPR) were less likely to indicate a preference for receiving CPR in the event of an in-hospital cardiac arrest than ...
Other
Dec 10, 2012 |
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