Rockefeller University
A culprit behind brain tumor resistance to therapy
Persistent protein expression may explain why tumors return after therapy in glioblastoma patients, according to a study published on March 5th in the Journal of Experimental Medicine.
Cancer
Mar 05, 2012 |
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How autoreactive T cells slip through the cracks
Immune cells capable of attacking healthy organs "see" their targets differently than do protective immune cells that attack viruses, according to work published online this week in the Journal of Experimental Medicine.
Medical research
Feb 06, 2012 |
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Detailed picture of how myoV 'walks' along actin tracks
A new study in the Journal of General Physiology uses state-of-the-art fluorescence microscopy to provide a striking 3-D picture of how class V myosins (myoV) "walk" along their actin track.
Medical research
Jan 30, 2012 |
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Study of fruit fly sleep reveals a genetic basis of insomnia
(Medical Xpress) -- On the surface, it’s simple: when night falls, our bodies get sleepy. But behind the scenes, a series of complex molecular events, controlled by our genes, is hard at work to make ...
Neuroscience
Jan 30, 2012 |
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Selectively inhibiting PKM2 starves cancer cells
Crippling a protein that allows cancer cells to grow when oxygen is scarce causes tumors to regress, according to a study published online on January 23 in the Journal of Experimental Medicine.
Cancer
Jan 23, 2012 |
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A single therapy slows multiple cancers
Targeting a single protein can help fight both breast cancers and leukemias, according to two reports published online on January 23 in the Journal of Experimental Medicine.
Cancer
Jan 23, 2012 |
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DGK-alpha helps cancer cells gain traction and mobilize
Metastasizing cancer cells often express integrins that provide better traction. A new study in The Journal of Cell Biology reveals how a lipid-converting enzyme helps the cells mobilize these integrins.
Cancer
Jan 23, 2012 |
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A firmer understanding of muscle fibrosis
Researchers describe how increased production of a microRNA promotes progressive muscle deterioration in a mouse model of Duchenne muscular dystrophy (DMD), according to a study published online on January ...
Medical research
Jan 02, 2012 |
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First 'live' imaging of specialized immune system cells reveals new clues about body's security system
To keep the body safe, the immune system enlists more than one form of protection. A circulating task force of immune system cells monitors the body’s periphery, and sends information back to field command centers — ...
Medical research
Dec 21, 2011 |
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In cancer, molecular signals that recruit blood vessels also trigger metastasis
(Medical Xpress) -- Cancer cells are most deadly when they’re on the move — able not only to destroy whatever organ they are first formed in, but also to create colonies elsewhere in the body. New ...
Cancer
Dec 19, 2011 |
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Two-faced leukemia?
One kind of leukemia sometimes masquerades as another, according to a study published online this week in the Journal of Experimental Medicine.
Cancer
Dec 12, 2011 |
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Simple, model-free analysis of voltage-gated channels
A new study in the Journal of General Physiology provides fresh insight into voltage-gated channels—transmembrane ion channels that play a critical role in the function of neuronal and muscle tissue.
Medical research
Dec 12, 2011 |
5 / 5 (1) |
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What wakes dormant tumor cells
Prostate tumor cells can be lulled to sleep by a factor released by bone cells, according to a study published online this week in the Journal of Experimental Medicine. Disease recurs in up to half of prostate cancer patien ...
Cancer
Nov 28, 2011 |
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Poor recycling of BACE1 enzyme could promote Alzheimer's disease
Sluggish recycling of a protein-slicing enzyme could promote Alzheimer's disease, according to a study published online on November 21 in The Journal of Cell Biology.
Medical research
Nov 21, 2011 |
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Statin-intolerant patients need a different type of clinical trial
(Medical Xpress) -- Millions of people take statins, the blockbuster drug that lowers low-density lipoprotein (LDL), the so-called bad cholesterol. But as many as 20 percent of them develop adverse effects such as muscle ...
Medical research
Nov 18, 2011 |
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