Rockefeller University

How developing sperm stick to the right path

The process of producing high-quality, fertile sperm requires many steps. A study in The Journal of Cell Biology shows how the transcription factor p73 promotes this process by regulating the adhesions betwee ...

Mar 24, 2014
popularity 5 / 5 (1) | comments 0

p53 cuts off invading cancer cells

The tumor suppressor p53 does all it can to prevent oncogenes from transforming normal cells into tumor cells by killing defective cells or causing them to become inactive. Sometimes oncogenes manage to initiate ...

Mar 24, 2014
popularity 5 / 5 (1) | comments 0

Gut microbes spur development of bowel cancer

It is not only genetics that predispose to bowel cancer; microbes living in the gut help drive the development of intestinal tumors, according to new research in mice published in the March issue of The Jo ...

Mar 03, 2014
popularity 5 / 5 (10) | comments 0

Protecting the skin from sun exposure

The ultraviolet radiation (UVR) present in sunlight is the most common environmental carcinogen, and long-term exposure to UVR can lead to skin cancer and premature aging of the skin. To develop better methods ...

Jan 27, 2014
popularity 5 / 5 (1) | comments 0

A trigger for muscular diseases

A University of Arizona doctoral candidate has shown for the first time that genetic mutations in the titin gene can cause skeletal muscle myopathy, a disease in which muscle fibers do not function properly, ...

Jan 27, 2014
popularity 5 / 5 (2) | comments 0 | with audio podcast

FAK helps tumor cells enter the bloodstream

Cancer cells have something that every prisoner longs for—a master key that allows them to escape. A study in The Journal of Cell Biology describes how a protein that promotes tumor growth also enables cancer ...

Jan 20, 2014
popularity 5 / 5 (2) | comments 0 | with audio podcast

Nicotine exploits COPI to foster addiction

A study in The Journal of General Physiology helps explain how nicotine exploits the body's cellular machinery to promote addiction. The findings could lead to new therapies to help people quit smoking.

Dec 30, 2013
popularity not rated yet | comments 0 | with audio podcast