Rockefeller University

Stay-at-home transcription factor prevents neurodegeneration

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow ...

Medical research created Oct 29, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Helping ex-smokers resist the urge

A new inhibitor helps previously nicotine-addicted rats stay on the wagon, according to a study published on October 22nd in the Journal of Experimental Medicine.

Addiction created Oct 22, 2012 | popularity not rated yet | comments 1

Kinesin 'chauffeur' helps HIV escape destruction

A study in The Journal of Cell Biology identifies a motor protein that ferries HIV to the plasma membrane, helping the virus escape from macrophages.

HIV & AIDS created Oct 22, 2012 | popularity not rated yet | comments 0

Sugar-free approach to treating Kaposi sarcoma

A sugar-loving protein drives the growth of Kaposi sarcoma (KS) tumors, according to a study published on October 1st in The Journal of Experimental Medicine. Interfering with these sugary interactions inhibited growth of Kap ...

Cancer created Oct 01, 2012 | popularity not rated yet | comments 0

Fitting Kv potassium channels in the PIP2 puzzle

A recent study in the Journal of General Physiology brings new insights to an area of ion channel regulation: whether voltage-gated potassium (Kv) channels can be regulated by physiological changes to PIP ...

Medical research created Aug 27, 2012 | popularity not rated yet | comments 0

Protein proves to be vital in immune response to bacteria

(Medical Xpress) -- A team of researchers led by scientists at Rockefeller University have discovered that a protein once thought to be mainly involved in antiviral immunity is in fact more important in ...

Medical research created Aug 13, 2012 | popularity not rated yet | comments 0 | with audio podcast

Collaboration finds kidney disease tied to DNA damage

(Medical Xpress) -- A research collaboration involving Rockefeller University and more than two dozen other institutions has found a link between a gene mutation and chronic kidney failure. The study, published ...

Genetics created Aug 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Starr collaboration illuminates mysterious pathway to immortality in cancer cells

(Medical Xpress) -- Cancer cells are immortal because they circumvent failsafe mechanisms that stop out-of-control cell proliferation. One of these mechanisms – the progressive shortening of chromosomes ...

Cancer created Jul 25, 2012 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Sweat glands grown from newly identified stem cells

To date, few fundamentals have been known about the most common gland in the body, the sweat glands that are essential to controlling body temperature, allowing humans to live in the world’s diverse climates. ...

Medical research created Jul 06, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Rockefeller scientists pioneer new method to determine mechanisms of drug action

(Medical Xpress) -- Knowing that a drug works is great. Knowing how it works is a luxury. And until now, determining a drug’s mechanism of action has been a tedious and difficult process for scientists.

Medical research created May 25, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

How Parkinson's disease starts and spreads

Injection of a small amount of clumped protein triggers a cascade of events leading to a Parkinson's-like disease in mice, according to an article published online this week in the Journal of Experimental Medicine.

Parkinson's & Movement disorders created Apr 16, 2012 | popularity 5 / 5 (1) | comments 0

Getting down to the heart of the (gray) matter to treat Parkinson's disease

An agent under consideration for use in PET imaging combats neuronal death to relieve Parkinsonian symptoms in animal models, according to a study published on April 2nd in the Journal of Experimental Medicine.

Parkinson's & Movement disorders created Apr 02, 2012 | popularity 5 / 5 (2) | comments 0

Breaking the backbone of triple-negative breast cancers

Putting the brakes on an abundant growth-promoting protein causes breast tumors to regress, according to a study published on March 19th in the Journal of Experimental Medicine.

Cancer created Mar 19, 2012 | popularity not rated yet | comments 0

Influenza 'histone mimic' suppresses antiviral response

(Medical Xpress) -- For a virus like influenza, the key to success isn't in overpowering the immune system, it’s in tricking it. A team of researchers led by scientists at The Rockefeller University has ...

Medical research created Mar 14, 2012 | popularity 2 / 5 (2) | comments 0 | with audio podcast

Lasting T cell memories

The generation of new memories in the human immune system doesn't come at the cost of old ones, according to a study published on March 5th in the Journal of Experimental Medicine.

Immunology created Mar 05, 2012 | popularity 5 / 5 (1) | comments 0