Of enzymes and aging: Tryptophan metabolism plays key role in aging and age-related neurological diseases
(Medical Xpress)—In the battle against aging and age-related neurological diseases such as Parkinson's and Alzheimer's, a key factor has long appeared to be the toxicity of proteins which tend to aggregate. ...
Medical research
Oct 05, 2012 |
4.7 / 5 (14) |
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Rice opens new window on Parkinson's disease
(Medical Xpress)—Rice University scientists have discovered a new way to look inside living cells and see the insoluble fibrillar deposits associated with Parkinson's disease.
Parkinson's & Movement disorders
Dec 17, 2012 |
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New clue to Parkinson's: Shape of key protein surprises researchers
A new study finds that a protein key to Parkinson's disease has likely been mischaracterized. The protein, alpha-synuclein, appears to have a radically different structure in healthy cells than previously thought, challenging ...
Medical research
Aug 14, 2011 |
4.8 / 5 (17) |
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Study reveals probable role of Parkinson's protein in healthy brain
(Medical Xpress)—Researchers at the Stanford University School of Medicine have exposed the possible function, in the healthy brain, of a mysterious molecule that has been strongly implicated in Parkinson's ...
Parkinson's & Movement disorders
May 01, 2013 |
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Research shows genetic evidence that new therapies targeting Parkinson's disease may cause harm
(Medical Xpress)—NorthShore University HealthSystem (NorthShore) and Mayo Clinic researchers have partnered on a study that shows genetic and clinical evidence that therapies targeting the expression of alpha-synuclein—a ...
Parkinson's & Movement disorders
Mar 21, 2013 |
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Scientists identify 'clean-up' snafu that kills brain cells in Parkinson's disease
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells. The study, which published online today in ...
Parkinson's & Movement disorders
Mar 03, 2013 |
5 / 5 (2) |
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Excess protein linked to development of Parkinson's disease
Researchers at the University of California, San Diego School of Medicine say overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons, starting with the ...
Parkinson's & Movement disorders
Feb 07, 2013 |
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Parkinson's protein causes disease spread in animal model, suggesting way disorder progresses over time in humans
(Medical Xpress) -- Penn researchers have shown that brain tissue from a Parkinson's disease mouse model , as well as synthetically produced disease protein fibrils, injected into young, symptom-free PD mice ...
Parkinson's & Movement disorders
Apr 17, 2012 |
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Curcumin shows promise in attacking Parkinson's disease
Curcumin, a compound found in the spice turmeric, is proving effective at preventing clumping of a protein involved in Parkinson's disease, says a Michigan State University researcher.
Parkinson's & Movement disorders
Mar 20, 2012 |
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Seeds of destruction in Parkinson's disease: Spread of diseased proteins kills neurons
New research suggests that small "seed" amounts of diseased brain proteins can be taken up by healthy neurons and propagated within them to cause neurodegeneration. The research, published by Cell Press in the October 6 issue ...
Neuroscience
Oct 05, 2011 |
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Rare genetic disorder provides unique insight into Parkinson's disease
Massachusetts General Hospital investigators appear to have found the mechanism behind a previously reported link between the rare genetic condition Gaucher disease and the common neurodegenerative disorder Parkinson's disease. ...
Genetics
Jun 23, 2011 |
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Copper folds protein into precursors of Parkinson's plaques
Researchers at North Carolina State University have figured out how copper induces misfolding in the protein associated with Parkinson's disease, leading to creation of the fibrillar plaques which characterize the disease. ...
Medical research
Jun 14, 2011 |
5 / 5 (4) |
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Mechanism that leads to sporadic Parkinson's disease identified
Researchers in the Taub Institute at Columbia University Medical Center (CUMC) have identified a mechanism that appears to underlie the common sporadic (non-familial) form of Parkinson's disease, the progressive movement ...
Parkinson's & Movement disorders
Sep 25, 2012 |
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Colonoscopy or flexible sigmoidoscopy may be used to predict Parkinson's
Two studies by neurological researchers at Rush University Medical Center suggest that, in the future, colonic tissue obtained during either colonoscopy or flexible sigmoidoscopy may be used to predict who will develop Parkinson's ...
Parkinson's & Movement disorders
May 15, 2012 |
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Study first to link mitochondrial dysfunction and alpha-Synuclein multiplication in human fibroblasts
A new study in the Journal of Parkinson's Disease shows for the first time the effects of α-Synuclein (α-syn) gene multiplication on mitochondrial function and susceptibility to oxidative stress in human tissue ...
Diseases, Conditions, Syndromes
Oct 06, 2011 |
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