News tagged with angiogenesis

A coordinated response to cardiac stress

Myocardial hypertrophy, a thickening of the heart muscle, is an adaptation that occurs with increased stress on the heart, such as high blood pressure. As the heart muscle expands, it also requires greater blood flow to maintain ...

Cardiology created Mar 01, 2013 | popularity not rated yet | comments 0

Researchers link stress and pancreatic cancer in new paper

Pancreatic cancer is a deadly disease with increased incidences in the recent years. According to NDSU researchers, epidemiological data show chronic stress in a negative social and psychological state such as depression ...

Cancer created Feb 15, 2013 | popularity 5 / 5 (3) | comments 0

Research uncovers new protein to treat damaged bones

Korean researchers believe that the 'DJ-1 protein' can be used to promote the formation of new bone tissue in patients suffering from osteoporosis by improving communication between bone making cells (osteoblasts) ...

Medical research created Jan 10, 2013 | popularity 5 / 5 (1) | comments 0

Improving chemotherapy effectiveness by acting on the immune system

An Inserm team in Dijon directed by François Ghiringhelli is to publish an article this week in the Nature Medicine review. The article suggests that two chemotherapy drugs frequently used to treat digestive and breast cancers ...

Immunology created Dec 04, 2012 | popularity not rated yet | comments 0

Combination treatment may improve survival of breast cancer patients with brain metastases

Adding an angiogenesis inhibitor to treatment with a HER2-inhibiting drug could improve outcomes for patients with HER2-positive breast cancer who develop brain metastases. In their report published online in PNAS Plus, ...

Cancer created Nov 01, 2012 | popularity not rated yet | comments 0

How the fluid between cells affects tumors

There are many factors that affect tumor invasion, the process where a tumor grows beyond the tissue where it first developed. While factors like genetics, tissue type and environmental exposure affect tumor ...

Cancer created Jul 25, 2012 | popularity not rated yet | comments 0

Scientists develop mouse model that could lead to new therapies for liver cancer

Researchers have created the first mouse model demonstrating the role of a cancer promoting gene, Astrocyte elevated gene-1 (AEG-1), in hepatocellular carcinoma, or liver cancer. The mouse model represents a critical step ...

Cancer created Jul 06, 2012 | popularity not rated yet | comments 0

Some stem cells can trigger tumors

(Medical Xpress) -- Stem cells often used in reconstructive surgery following mastectomies and other cancer-removal treatments may pose a danger: Cornell biomedical scientists have discovered that these cells, ...

Cancer created Jun 05, 2012 | popularity 5 / 5 (1) | comments 0

Breast cancer effectively treated with chemical found in celery

Apigenin, a natural substance found in grocery store produce aisles, shows promise as a non-toxic treatment for an aggressive form of human breast cancer, following a new study at the University of Missouri. MU researchers ...

Cancer created May 16, 2012 | popularity 3.5 / 5 (2) | comments 0

Study finds an on-off switch for angiogenesis

Scientists from the MIRA and MESA+ research institutes at the University of Twente (The Netherlands) have discovered an ‘on/off switch’ for angiogenesis in human tissue. Their research has shown ...

Medical research created Apr 27, 2012 | popularity not rated yet | comments 0

Novel bioactive peptides promote wound healing in vivo

Researchers have combined bioactive peptides to successfully stimulate wound healing. The in vitro and in vivo study, published today in PLoS ONE, demonstrates that the combination of two peptides stimulates the growth of blo ...

Medical research created Feb 24, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Essential protein for the formation of new blood vessels identified

New research explains how cells regulate their bonds during the development of new blood vessels. For the first time, the role of the protein Raf-1 in determining the strength of the bond between cells has ...

Medical research created Jan 17, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Blood protein EPO involved in origin and spread of cancer

Researchers at the Swedish medical university Karolinska Institutet have demonstrated that a growth hormone, PDGF-BB, and the blood protein EPO are involved in the development of cancer tumours and that they combine to help ...

Cancer created Dec 05, 2011 | popularity not rated yet | comments 1 | with audio podcast

Combination therapy shows potent tumor growth inhibition in preclinical studies

Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC ...

Cancer created Nov 13, 2011 | popularity not rated yet | comments 0

Scientists identify a key molecule that blocks abnormal blood vessel growth in tumors

A new and better understanding of blood vessel growth and vascular development (angiogenesis) in cancer has been made possible by research carried out by a team of scientists from Moffitt Cancer Center, the University of ...

Medical research created Sep 21, 2011 | popularity not rated yet | comments 0 | with audio podcast

Angiogenesis

Angiogenesis is the physiological process involving the growth of new blood vessels from pre-existing vessels. Though there has been some debate over terminology, vasculogenesis is the term used for spontaneous blood-vessel formation, and intussusception is the term for the formation of new blood vessels by the splitting of exisiting ones.

Angiogenesis is a normal and vital process in growth and development, as well as in wound healing and in granulation tissue. However, it is also a fundamental step in the transition of tumors from a dormant state to a malignant one, leading to the use of angiogenesis inhibitors. The identification of an angiogenic diffusible factor derived from tumors was made initially by Greenblatt and Shubik in 1968.

For more information about Angiogenesis, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: blood vessels