Immunology

Autoimmune disorders found to affect around 1 in 10 people

A new population-based study of 22 million people shows that autoimmune disorders now affect about 1 in 10 individuals. The work, published in The Lancet, also highlights important socioeconomic, seasonal, and regional differences ...

Immunology

A common metabolite may help treat autoimmune diseases

Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.

Diseases, Conditions, Syndromes

Lupus pill shows promise in mice; clinical trial underway

Lupus is an autoimmune disease that attacks organs and can be fatal. There's no cure, so current treatments aim to limit damage and ameliorate symptoms. Some of these therapies have to be injected, some have serious side ...

Immunology

How the thymus trains T cells to fight infections

T cells are a special class of white blood cells that patrol the body and attack infected or foreign tissue. They learn to distinguish friendly proteins from dangerous ones in an organ called the thymus. However, when T cells ...

Medical research

How gut microbes can evolve and become dangerous

Gut microbes have been linked to both good health and the promotion of diseases such as autoimmune disorders, inflammatory bowel diseases, metabolic syndrome, and even neuropsychiatric disorders.

Genetics

Exploring autoimmunity's regulatory roots

Our genome contains vast networks that regulate the activity of protein-coding genes. Variations in this regulatory DNA (which does not encode proteins) may affect both when and how much of a given protein a cell produces. ...

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