News tagged with b cell
A more complicated network than generally accepted may control maturation of B cells in the immune system
The process of blood cell development, known as hematopoiesis, gives rise to numerous different immune cell subtypes. Each of these in turn matures through a stepwise process governed by the action of transcription ...
Medical research
Nov 22, 2012 |
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How defects in a signaling protein sabotage the immune system in multiple, seemingly contradictory ways
The antibody response to immune threats is managed by cells known as B lymphocytes. The differentiation and function of B cells are tightly regulated to ensure a prompt response to confirmed dangers, such ...
Immunology
Nov 21, 2012 |
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Rituximab shows promise for clinical problems tied to antiphospholipid antibodies
Rituximab, a drug used to treat cancer and arthritis, may help patients with antiphospholipid antibodies (aPLs) who suffer from aPL-related clinical problems that do not respond to anticoagulation, such as cardiac disease ...
Arthritis & Rheumatism
Nov 20, 2012 |
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Multiple sclerosis 'immune exchange' between brain and blood is uncovered
DNA sequences obtained from a handful of patients with multiple sclerosis at the University of California, San Francisco (UCSF) Medical Center have revealed the existence of an "immune exchange" that allows the disease-causing ...
Medical research
Nov 19, 2012 |
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Effects of alcohol on lymphoma, leukemia, and other types of hematological cancers
Many observational epidemiologic studies have found an inverse association between alcohol consumption and hematological cancers (such as lymphoma and leukemia). This study, based on the Million Women's Study in the UK, is ...
Cancer
Nov 13, 2012 |
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Genome sequencing of Burkitt Lymphoma reveals unique mutation
In the first broad genetic landscape mapped of a Burkitt lymphoma tumor, scientists at Duke Medicine and their collaborators identified 70 mutations, including several that had not previously been associated with cancer and ...
Genetics
Nov 12, 2012 |
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How infection can trigger autoimmune disease
Australian scientists have confirmed a 'weak link' in the immune system – identifying the exact conditions under which an infection can trigger an autoantibody response, a process not clearly understood until now.
Immunology
Nov 09, 2012 |
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Scientists identify new target for lung cancer treatment
A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed ...
Cancer
Nov 01, 2012 |
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After three decades of searching, scientists find cellular targets of Hepatitis B virus
A University of Colorado Boulder-led team has discovered two prime targets of the Hepatitis B virus in liver cells, findings that could lead to treatment of liver disease in some of the 400 million people worldwide currently ...
Diseases, Conditions, Syndromes
Oct 22, 2012 |
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Vitamin D supplements may benefit lupus patients
A new clinical study published in BioMedCentral's open access journal Arthritis Research and Therapy provides preliminary evidence that vitamin D supplementation could be considered an immunomodulatory agent for systemic lupus ...
Arthritis & Rheumatism
Oct 16, 2012 |
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Finding the origins of infant leukaemia
Leukaemia arises as a result of genetic or epigenetic alterations in blood cells, leading to an aberrant accumulation of undifferentiated blasts. Understanding the molecular pathogenesis and aetiology of ...
Cancer
Oct 15, 2012 |
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Rare B cells regulate immune responses, may offer novel treatment for autoimmune diseases
Reproducing a rare type of B cell in the laboratory and infusing it back into the body may provide an effective treatment for severe autoimmune diseases such as multiple sclerosis or rheumatoid arthritis, according to researchers ...
Medical research
Oct 14, 2012 |
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How the body uses vitamin B to recognize bacterial infection
An Australian research team has discovered how specialised immune cells recognise products of vitamin B synthesis that are unique to bacteria and yeast, triggering the body to fight infection.
Medical research
Oct 10, 2012 |
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Solving puzzle of B-cell lymphoma development
Germinal centers are sites in the organs of the lymphatic system, formed during the course of an immune response to infection, where B cells intensely proliferate and modify their DNA in order to produce ...
Immunology
Sep 23, 2012 |
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Earlier treatment for young patients with chronic hepatitis B more effective in clearing virus
Scientists from A*STAR's Singapore Institute for Clinical Sciences (SICS), together with clinical collaborators from London , discovered for the first time that children and young patients with chronic Hepatitis B Virus infection ...
Diseases, Conditions, Syndromes
Sep 06, 2012 |
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