In treating aggressive lymphomas and blood cancer (leukemia), chimeric antigen receptor T cells (CAR T cells) are increasingly being used. For this therapy, immune cells are taken from patients and programmed by means of ...
Feb 9, 2024
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A novel high-throughput screening assay is designed to identify inhibitors of the androgen receptor, which plays a critical role in the progression of prostate cancer. The assay could be used to identify new drugs to treat ...
Apr 6, 2022
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In the spring of 2020, Université de Montréal biochemistry professor Christian Baron had an idea: Why not evaluate the inhibition capacity of a commercially available molecule called VE607 on the virus causing COVID-19?
Feb 10, 2022
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A molecular study published today in Science reveals how the mutations in delta and kappa variants of the pandemic coronavirus help the variants avoid recognition by antibodies.
Nov 9, 2021
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For years, scientists have struggled to find a way to block a protein known to play an important role in many cancers. The protein, STAT3, acts as a transcription factor—it performs the crucial task of helping convert DNA ...
Nov 19, 2015
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Researchers at UC Santa Cruz have determined the structure of a key part of the enzyme telomerase, which is active in most cancers and enables cancer cells to proliferate indefinitely. The new findings, published October ...
Oct 5, 2015
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(Medical Xpress)—Scientists from the FMI identify how a family of proteins reads the methylation marks on the DNA so critical for cell development. These MBD proteins bind directly to methylation marks and inactivate the ...
Apr 12, 2013
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Medical researchers at the University of Sheffield have defined the structure of a key part of the human obesity receptor- an essential factor in the regulation of body fat- which could help provide new treatments for the ...
Apr 27, 2012
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A recent study led by Gergely Lukacs, a professor at McGill University's Faculty of Medicine, Department of Physiology, and published in the January issue of Cell, has shown that restoring normal function to the mutant gene ...
Mar 12, 2012
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