News tagged with biological mechanisms
New target for treating wide spectrum of cancers
(Medical Xpress)—UC Irvine biologists, chemists and computer scientists have identified an elusive pocket on the surface of the p53 protein that can be targeted by cancer-fighting drugs. The finding heralds a new treatment ...
Cancer
Jan 31, 2013 |
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Researchers identify possible drug target in breast cancer metastasis
The spread of breast cancer to distant organs within the body, an event that often leads to death, appears in many cases to involve the loss of a key protein, according to UC San Francisco researchers, whose new discoveries ...
Cancer
Jan 27, 2013 |
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Circadian rhythms can be modified for potential treatment of disorders
(Medical Xpress)—UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms – also known as the body clock – modify energy metabolism and also have identified novel compounds that control ...
Cardiology
Jan 22, 2013 |
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Cancer biology: Keeping bad company
The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of ...
Cancer
Jan 16, 2013 |
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Scientists reveal aggressive breast cancer's metastatic path
Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor ...
Cancer
Jan 14, 2013 |
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Rhythms in the brain help give a sense of location, study shows
Research at the University of Edinburgh tracked electrical signals in the part of the brain linked to spatial awareness.
Neuroscience
Jan 10, 2013 |
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Multiple sclerosis drug may one day treat colorectal cancer
After uncovering a mechanism that promotes chronic intestinal inflammation and the development of colorectal cancer, scientists from Virginia Commonwealth University Massey Cancer Center have found that fingolimod, ...
Cancer
Jan 09, 2013 |
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Healthy BMI levels, physical activity linked to endometrial cancer survival
(Medical Xpress)—Higher body mass index (BMI) and physical inactivity are associated with more than a two-fold increase in risk for mortality among women with endometrial cancer, new research by the Yale ...
Cancer
Jan 08, 2013 |
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Inherited retinal disease research may lead to treatment
Inherited retinal disease is a major cause of vision impairment in early life - and a researcher at The University of Western Australia hopes a study in which he was involved will contribute towards the development ...
Medical research
Jan 08, 2013 |
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New study finds key mechanism in calcium regulation
All living cells keep their cellular calcium concentration at a very low level. Since a small increase in calcium can affect many critical cellular functions (an elevated calcium concentration over an extended period can ...
Neuroscience
Jan 03, 2013 |
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The factor that could influence future breast cancer treatment
Australian scientists have shown in the laboratory how a 'transcription factor' causes breast cancer cells to develop an aggressive subtype that lacks sensitivity to estrogen and does not respond to known anti-estrogen therapies. ...
Cancer
Dec 27, 2012 |
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FDA: Pradaxa not for patients with mechanical heart valves
(HealthDay)—The blood thinner Pradaxa should not be used to prevent stroke or blood clots in patients with mechanical heart valves, the U.S. Food and Drug Administration said in a warning issued Wednesday.
Cardiology
Dec 21, 2012 |
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Research pinpoints key gene for regenerating cells after heart attack
UT Southwestern Medical Center researchers have pinpointed a molecular mechanism needed to unleash the heart's ability to regenerate, a critical step toward developing eventual therapies for damage suffered following a heart ...
Medical research
Dec 20, 2012 |
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Toasting your health: Take care with alcohol consumption
(Medical Xpress)—The holidays are a time to consume—food, gifts, and spirits. Here are a few alcohol-related story ideas from The Methodist Hospital. Because alcohol's effects on human physiology are complex, advice about ...
Health
Dec 20, 2012 |
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Protein kinase Akt identified as arbiter of cancer stem cell fate, paper reports
(Medical Xpress)—The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author ...
Cancer
Dec 20, 2012 |
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