Gene therapy can correct forms of severe combined immunodeficiency
Severe combined immunodeficiency is defect in the immune system that results in a loss of the adaptive immune cells known as B cells and T cells. Mutations in several different genes can lead to the development of severe ...
Immunology
May 24, 2012 |
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Stem-cell-growing surface enables bone repair
(Medical Xpress) -- University of Michigan researchers have proven that a special surface, free of biological contaminants, allows adult-derived stem cells to thrive and transform into multiple cell types. ...
Medical research
May 23, 2012 |
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Hormone plays surprise role in fighting skin infections
Antimicrobial peptides (AMPs) are molecules produced in the skin to fend off infection-causing microbes. Vitamin D has been credited with a role in their production and in the body's overall immune response, ...
Medical research
May 23, 2012 |
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Heparin-like compounds inhibit breast cancer metastasis to bone
Researchers from VTT Technical Research Centre of Finland have in collaboration with the University of Turku, Indiana University and two Finnish companies, Biotie Therapies Corp. and Pharmatest Services Ltd, discovered a ...
Cancer
May 21, 2012 |
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Stabilizing Fanconi anemia with antioxidants
Fanconi anemia (FA) is a rare genetic disorder which affects one person in 350,000. People affected by this disease have defects in DNA repair, and are hypersensitive to oxidative damage, resulting in bone marrow failure ...
Diseases, Conditions, Syndromes
May 15, 2012 |
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Drugs reduce bone cancer damage but clinical guidance remains non-specific
Bone cancer-related fractures and pain can be reduced by drug treatment, but no one drug is superior, according to a review published in The Cochrane Library. Researchers undertook a systematic review of the current eviden ...
Cancer
May 15, 2012 |
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SCAI: Ixmyelocel-T studied for dilated cardiomyopathy
(HealthDay) -- For patients with dilated cardiomyopathy, treatment with an autologous bone marrow-derived, expanded multi-cell product, ixmyelocel-T, is well tolerated and associated with improved symptoms ...
Cardiology
May 15, 2012 |
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'Fertilizing' bone marrow helps answer why some cancers spread to bones
Researchers found that administering a common chemotherapy drug before bone tumors took root actually fertilized the bone marrow, enabling cancer cells, once introduced, to seed and grow more easily.
Cancer
May 15, 2012 |
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Scientists grow bone from human embryonic stem cells
As people live longer, repairing or regenerating human tissues has become an ever-more critical issue. Just in the past decade alone, human stem cells are emerging as powerful tools for tissue regeneration, as they can differentiate ...
Medical research
May 14, 2012 |
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Researchers use dual strategy to fight Type 1 diabetes
(Medical Xpress) -- University of Florida researchers teamed with colleagues at City of Hope National Medical Center in Duarte, Calif., to devise a new combination therapy that reverses established Type 1 diabetes in mice.
Medical research
May 10, 2012 |
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Gene-modified stem cell transplant protects patients from toxic side effects of chemotherapy
For the first time, scientists at Fred Hutchinson Cancer Research Center have transplanted brain cancer patients' own gene-modified blood stem cells in order to protect their bone marrow against the toxic side effects of ...
Cancer
May 09, 2012 |
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Rituximab promotes long-term response for patients with immune destruction of platelets
A new analysis concludes that rituximab, a drug commonly used to treat blood cancers, leads to treatment responses lasting at least five years in approximately one quarter of patients with low platelet counts and a risk of ...
Pediatrics
May 07, 2012 |
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Mechanism ID'd for benefit of stem cells in autoimmunity
(HealthDay) -- Bone marrow mesenchymal stem cells (BMMSCs) activate a mechanism involving coupling of FAS/FAS ligand to induce T cell apoptosis and immune tolerance, according to an experimental study published ...
Medical research
May 02, 2012 |
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High-strength silk scaffolds improve bone repair
Biomedical engineers at Tufts University's School of Engineering have demonstrated the first all-polymeric bone scaffold material that is fully biodegradable and capable of providing significant mechanical support during ...
Medical research
Apr 30, 2012 |
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Leukaemia cells have a remembrance of things past
Although people generally talk about "cancer", it is clear that the disease occurs in a bewildering variety of forms. Even single groups of cancers, such as those of the white blood cells, may show widely differing properties. ...
Cancer
Apr 24, 2012 |
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