Medical research
A safer opioid? Scientists are onto something
Sodium may hold the key for scientists to develop opioids or other drugs with far fewer side effects.
Nov 30, 2022
1
46
News tagged with cancer drug development
Medical research
A link between hypoxia and fetal hemoglobin provides hope for sickle cell disease
Scientists at St. Jude Children's Research Hospital have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased expression of fetal hemoglobin (HbF) in adults. The finding has implications ...
Oct 12, 2022
0
50
Oncology & Cancer
New classification system proposed for colorectal cancer to guide treatment and clinical trials
A team of clinician-scientists and scientists, led by the National Cancer Centre Singapore (NCCS) and A*STAR's Genome Institute of Singapore (GIS) together with collaborators in Europe and South Korea, used single cell techniques ...
Jul 1, 2022
0
65
Oncology & Cancer
Genome-wide intricacies of cancer inhibitor untangled
A newly discovered inhibitor of a common cancer-causing protein operates selectively, reducing expression of genes that fuel rampant cell proliferation and alter the epigenome, according to a Northwestern Medicine study published ...
Jun 6, 2022
0
52
Oncology & Cancer
New database to 'SpUR' on cancer research
An interactive web portal developed by scientists at KAUST offers a platform for cancer researchers to interrogate how RNA splicing in noncoding parts of genes fuels the growth of different types of tumors.
May 26, 2022
0
54
Oncology & Cancer
3D tissue model of living brain cancer points to possible future for drug screening
As a potential alternative for drug testing without lab animals, researchers at KTH Royal Institute of Technology developed and successfully tested a 3D model of living brain cancer that surmounts one of the biggest challenges ...
Feb 23, 2022
0
69
Oncology & Cancer
Development of a new gastric cancer model: Identification of gastric cancer stem cells
Researchers have succeeded in establishing a mouse model that develops gastric cancer closely resembling advanced human gastric cancer. Using this model, they have discovered gastric cancer stem cells, i.e. Lgr5+ gastric ...
Dec 22, 2021
0
66
Immunology
CRISPR screen identifies new anti-inflammatory drug target
A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered. They report Nov. 11 in the ...
Nov 11, 2021
0
51
Alzheimer's disease & dementia
Cancer chemotherapy drug reverses Alzheimer's symptoms in mice
A drug commonly used to treat cancer can restore memory and cognitive function in mice that display symptoms of Alzheimer's disease, new UBC research has found.
Oct 5, 2021
1
270
Oncology & Cancer
First 3D-bioprinting of entire active tumor
Researchers at Tel Aviv University have printed an entire active and viable glioblastoma tumor using a 3D printer. The 3D-bioprinted tumor includes a complex system of blood vessel-like tubes through which blood cells and ...
Aug 18, 2021
0
620
