When treating a cancer patient, oncologists aim to predict the course of the patient's disease to make critical treatment decisions. Knowing a tumor's unique molecular signature can help guide these decisions by providing ...
Sep 23, 2021
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Every cell has two mechanisms for repairing DNA single- or double-strand breaks, which can be induced by such factors as environmental toxins, chemotherapy, or ionizing radiation. The first one consists of the DNA repair ...
Sep 21, 2022
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More than 200 genes with novel and known roles in glioblastoma—the most aggressive type of brain cancer—offer promising new drug targets. Researchers from the Wellcome Sanger Institute, Addenbrooke's Hospital and their ...
Jul 29, 2020
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Scientists studying a highly cancer-prone family have identified a rare, inherited gene mutation that dramatically raises the lifetime risk of pancreatic and other cancers.
Aug 12, 2019
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Two new discoveries led by Cedars-Sinai Cancer investigators help improve the understanding of what drives the development of ovarian cancer and why some women's tumors do not respond to therapy.
Oct 10, 2022
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The body's innate immune system, active from birth, is the first line of defense against viruses and other pathogens that cause disease. Using vaccination as an example, after receiving a vaccine, pain, redness, or swelling ...
May 25, 2022
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Scientists studying how genetics impact brain disease have long sought a better experimental model. Cultures of genetically-modified cell lines can reveal some clues to how certain genes influence the development of psychiatric ...
Oct 10, 2018
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Researchers at Vanderbilt University Medical Center have discovered a potential new target in the fight against colorectal cancer, the nation's third most common malignancy and, next to lung cancer, the second leading cancer ...
Jul 28, 2022
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Scientists with the Virginia Tech Carilion Research Institute say a gene involved in the body's circadian rhythms is a potential target for therapies to help patients with a deadly form of brain cancer known as glioblastoma.
Sep 11, 2018
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UCLA researchers have discovered a common process in the development of late-stage, small cell cancers of the prostate and lung. These shared molecular mechanisms could lead to the development of drugs to treat not just prostate ...
Oct 4, 2018
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