News tagged with cancer metastasis
Changing cancer's environment to halt its spread
By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces ...
Cancer
23 hours ago |
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Tumor-activated protein promotes cancer spread
Researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center report that cancers physically alter cells in the lymphatic system – a network of vessels that transports and ...
Cancer
May 13, 2013 |
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Decoded: Molecular messages that tell prostate and breast cancers to spread
Cancer cells are wily, well-traveled adversaries, constantly side-stepping treatments to stop their spread. But for the first time, scientists at the University of Michigan have decoded the molecular chatter that ramps certain ...
Cancer
Apr 30, 2013 |
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Battery of tests on cancer cells shows them as 'squishy,' yet tactically strong
A team of student researchers and their professors from 20 laboratories around the country have gotten a new view of cancer cells. The work could shed light on the transforming physical properties of these cells as they metastasize, ...
Cancer
Apr 26, 2013 |
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Metastasis stem cells in the blood of breast cancer patients discovered
Individual cancer cells that break away from the original tumor and circulate through the blood stream are considered responsible for the development of metastases. These dreaded secondary tumors are the ...
Cancer
Apr 22, 2013 |
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Study finds new drug target for metastatic breast cancer
Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the ...
Cancer
Apr 11, 2013 |
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Rigosertib Phase 1 results lead to disease-focused Phase 2 development
Results of a phase 1 clinical trial reported at the American Association for Cancer Research (AACR) annual conference show that orally administered Rigosertib is well tolerated in patients with advanced solid tumors. This ...
Cancer
Apr 09, 2013 |
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Six2 homeoprotein allows breast cancer cells to detach and metastasize
In results presented at the AACR Annual Meeting 2013, researchers from the University of Colorado Cancer Center show that the Six2 homeoprotein, while not involved in primary tumor growth, allows cells to detach from substrate ...
Cancer
Apr 09, 2013 |
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Little molecule makes big difference in bladder cancer metastasis
In order to kill, bladder cancer must metastasize, most commonly to the lung – what are the differences between bladder cancers that do and do not make this deadly transition? Research presented by the Director of the University ...
Cancer
Apr 09, 2013 |
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Third-generation device significantly improves capture of circulating tumor cells
A new system for isolating rare circulating tumor cells (CTCs) – living solid tumor cells found at low levels in the bloodstream – shows significant improvement over previously developed devices and does ...
Cancer
Apr 03, 2013 |
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Landmark study describes prostate cancer metastasis switch
Prostate cancer doesn't kill in the prostate – it's only once the disease travels to bone, lung, liver, etc. that it turns fatal. Previous studies have shown that loss of the protein E-Cadherin is essential for this metastasis. ...
Cancer
Apr 02, 2013 |
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In managing inflammation, controlling white blood cell flow may be key
(Medical Xpress)—New research by Yale University scientists sets the stage for improved management of acute tissue inflammation related to wounds and chronic inflammatory diseases by advancing current understanding ...
Inflammatory disorders
Mar 28, 2013 |
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Researcher examines mechanism underlying abdominal pain in pancreatic cancer
Erxi Wu, assistant professor of pharmaceutical sciences, co-wrote the article, "Neurotransmitter substance P mediates pancreatic cancer perineural invasion via NK-1R in cancer cells," which was published by Molecular Cancer Re ...
Cancer
Mar 01, 2013 |
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Study shows key enzyme missing from aggressive form of breast cancer
A groundbreaking new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain—providing insight ...
Cancer
Feb 28, 2013 |
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Researchers discover protein that may control the spread of cancer
Researchers at the University of Hawai'i Cancer Center have uncovered a novel mechanism that may lead to more selective ways to stop cancer cells from spreading. Associate Professor Joe W. Ramos PhD, a cancer biologist at ...
Cancer
Feb 26, 2013 |
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Metastasis
Metastasis (Greek: displacement, μετά=next + στάσις=placement, plural: metastases), or Metastatic disease, sometimes abbreviated mets, is the spread of a disease from one organ or part to another non-adjacent organ or part. Only malignant tumor cells and infections have the established capacity to metastasize; however, this is recently reconsidered by new research.
Cancer cells can break away, leak, or spill from a primary tumor, enter lymphatic and blood vessels, circulate through the bloodstream, and settle down to grow within normal tissues elsewhere in the body. Metastasis is one of three hallmarks of malignancy (contrast benign tumors). Most tumors and other neoplasms can metastasize, although in varying degrees (e.g., glioma and basal cell carcinoma rarely metastasize).
When tumor cells metastasize, the new tumor is called a secondary or metastatic tumor, and its cells are like those in the original tumor. This means, for example, that, if breast cancer metastasizes to the lungs, the secondary tumor is made up of abnormal breast cells, not of abnormal lung cells. The tumor in the lung is then called metastatic breast cancer, not lung cancer.
For more information about Metastasis, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.