News tagged with cancer metastasis

Limits to growth: Scientists identify key metastasis-enabling enzyme

(Medical Xpress) -- On the complex road to eradicating cancer, controlling or preventing metastatic growth initiated by primary tumors is high on the to-do list. A key area of such research is the development ...

Medical research created May 22, 2012 | popularity 4.3 / 5 (9) | comments 0 | with audio podcast feature

Race to the top: Decoding metastasis

(Medical Xpress) -- One of cancer's greatest and most insidious threats is metastasis – the three-dimensional migratory invasion of cancer cells from primary tumors to a distant part of the body. The ...

Cancer created Apr 29, 2011 | popularity 5 / 5 (12) | comments 0 | with audio podcast feature

Research breakthrough could halt melanoma metastasis

In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 ...

Cancer created Nov 14, 2012 | popularity 4.8 / 5 (6) | comments 0 | with audio podcast

Discovery reveals important clues to cancer metastasis

In recent years investigators have discovered that breast tumors are influenced by more than just the cancer cells within them. A variety of noncancerous cells, which in many cases constitute the majority ...

Cancer created Oct 11, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

LIFR protein suppresses breast cancer metastasis

A receptor protein suppresses local invasion and metastasis of breast cancer cells, the most lethal aspect of the disease, according to a research team headed by scientists from The University of Texas MD Anderson Cancer ...

Cancer created Sep 25, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

How breast cancer spreads: Researchers find key to lymph node metastasis in mice

The invasion of cancer cells into the lymph vessels that connect the breast to surrounding lymph nodes is the first step leading to the metastasis, or spread, of cancer throughout the body. Metastasis is the primary cause ...

Cancer created Sep 10, 2012 | popularity 4 / 5 (1) | comments 0

New synthetic molecules treat autoimmune disease in mice

A team of Weizmann Institute scientists has turned the tables on an autoimmune disease. In such diseases, including Crohn's and rheumatoid arthritis, the immune system mistakenly attacks the body's tissues. But the scientists ...

Immunology created Dec 25, 2011 | popularity 4.8 / 5 (8) | comments 0 | with audio podcast

Researchers show molecule inhibits metastasis of colon, melanoma cancers

Researchers at the Medical College of Wisconsin have shown that a protein can inhibit metastasis of colon and melanoma cancers. The findings are published in the October 10, 2011 issue of Proceedings of the National Academy of ...

Cancer created Oct 10, 2011 | popularity 5 / 5 (4) | comments 1 | with audio podcast

Brain cell migration during normal development may offer insight on how cancer cells spread

By shedding new light on how cells migrate in the developing brain, researchers at Fred Hutchinson Cancer Research Center also may have found a new mechanism by which other types of cells, including cancer cells, travel within ...

Neuroscience created Apr 24, 2011 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Tumor-activated protein promotes cancer spread

Researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center report that cancers physically alter cells in the lymphatic system – a network of vessels that transports and ...

Cancer created May 13, 2013 | popularity 4.2 / 5 (5) | comments 0 | with audio podcast

Decoded: Molecular messages that tell prostate and breast cancers to spread

Cancer cells are wily, well-traveled adversaries, constantly side-stepping treatments to stop their spread. But for the first time, scientists at the University of Michigan have decoded the molecular chatter that ramps certain ...

Cancer created Apr 30, 2013 | popularity not rated yet | comments 0 | with audio podcast

Battery of tests on cancer cells shows them as 'squishy,' yet tactically strong

A team of student researchers and their professors from 20 laboratories around the country have gotten a new view of cancer cells. The work could shed light on the transforming physical properties of these cells as they metastasize, ...

Cancer created Apr 26, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Metastasis stem cells in the blood of breast cancer patients discovered

Individual cancer cells that break away from the original tumor and circulate through the blood stream are considered responsible for the development of metastases. These dreaded secondary tumors are the ...

Cancer created Apr 22, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Third-generation device significantly improves capture of circulating tumor cells

A new system for isolating rare circulating tumor cells (CTCs) – living solid tumor cells found at low levels in the bloodstream – shows significant improvement over previously developed devices and does ...

Cancer created Apr 03, 2013 | popularity not rated yet | comments 0 | with audio podcast

Landmark study describes prostate cancer metastasis switch

Prostate cancer doesn't kill in the prostate – it's only once the disease travels to bone, lung, liver, etc. that it turns fatal. Previous studies have shown that loss of the protein E-Cadherin is essential for this metastasis. ...

Cancer created Apr 02, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Metastasis

Metastasis (Greek: displacement, μετά=next + στάσις=placement, plural: metastases), or Metastatic disease, sometimes abbreviated mets, is the spread of a disease from one organ or part to another non-adjacent organ or part. Only malignant tumor cells and infections have the established capacity to metastasize; however, this is recently reconsidered by new research.

Cancer cells can break away, leak, or spill from a primary tumor, enter lymphatic and blood vessels, circulate through the bloodstream, and settle down to grow within normal tissues elsewhere in the body. Metastasis is one of three hallmarks of malignancy (contrast benign tumors). Most tumors and other neoplasms can metastasize, although in varying degrees (e.g., glioma and basal cell carcinoma rarely metastasize).

When tumor cells metastasize, the new tumor is called a secondary or metastatic tumor, and its cells are like those in the original tumor. This means, for example, that, if breast cancer metastasizes to the lungs, the secondary tumor is made up of abnormal breast cells, not of abnormal lung cells. The tumor in the lung is then called metastatic breast cancer, not lung cancer.

For more information about Metastasis, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: cancer , cancer cells