Oncology & Cancer

Gene scissors find target for testicular cancer therapy

Researchers at the University Hospital Bonn (UKB) have now been able to elucidate a mechanism underlying cisplatin resistance in testicular cancer. Using CRISPR gene scissors, they identified the NAE1 gene as its driver. ...

Obstetrics & gynaecology

New technology to select healthier sperm for IVF success

Scientists have developed new technology to help couples undergoing in-vitro fertilization (IVF) due to male fertility problems to increase their chances of success in having a baby.

Medications

Another promising step toward non-hormonal male contraceptives

Despite birth control existing for decades, almost none of the options specifically target sperm cells. Researchers are now developing approaches that target testosterone or otherwise interrupt the sperm's ability to fertilize ...

Oncology & Cancer

Taming overactive molecular signaling in renal cell cancer

In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers driven by overexpression of the mechanistic target of rapamycin complex 1 (mTORC1) signaling ...

Oncology & Cancer

CDK4: A master regulator of the cell cycle and its role in cancer

The mammalian cell cycle is divided into four phases, Gap 1 (G1), Synthesis (S), Gap 2 (G2) and Mitosis (M), whose order and timing are critical for accurate transmission of genetic information. Consequently, a number of ...

page 3 from 22