Geneticists verify cholesterol-cancer link
University of Rochester Medical Center scientists discovered new genetic evidence linking cholesterol and cancer, raising the possibility that cholesterol medications could be useful in the future for cancer prevention or ...
Medical research
Sep 13, 2012 |
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Tension on gut muscles induces cell invasion in zebrafish intestine, mimicking cancer metastasis
The stiffness of breast tissue is increasingly recognized as an important factor explaining the onset of breast cancer. Stiffening induces molecular changes that promote cancerous behavior in cells. Bioengineering ...
Cancer
Sep 07, 2012 |
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Protein impedes microcirculation of malaria-infected red blood cells
(Medical Xpress)—When the parasite responsible for malaria infects human red blood cells, it launches a 48-hour remodeling of the host cells. During the first 24 hours of this cycle, a protein called RESA undertakes the ...
Medical research
Aug 30, 2012 |
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Genetic disease linked to protein build-up
Mutations of the gene Lmna previously thought to be directly responsible for a group of laminopathies—serious developmental conditions including premature aging and a form of muscular dystrophy—in fact ...
Medical research
Aug 29, 2012 |
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Fitting Kv potassium channels in the PIP2 puzzle
A recent study in the Journal of General Physiology brings new insights to an area of ion channel regulation: whether voltage-gated potassium (Kv) channels can be regulated by physiological changes to PIP ...
Medical research
Aug 27, 2012 |
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Cholesterol study points to new drugs
(Medical Xpress)—Insight into how our bodies make cholesterol could lead to treatments with fewer side-effects than existing drugs.
Cardiology
Aug 27, 2012 |
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It must be important but what does it do? The strange case of UCP2
When uncoupling proteins are active, mitochondria produce heat instead of ATP. This may be useful under certain circumstances, such as when an animal is hibernating. But non-hibernating animals also have them. Particularly ...
Medical research
Aug 17, 2012 |
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Antisense approach promising for treatment of parasitic infections
A targeted approach to treating toxoplasmosis, a parasitic disease, shows early promise in test-tube and animal studies, where it prevented the parasites from making selected proteins. When tested in newly infected mice, ...
Medical research
Aug 13, 2012 |
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Under the right conditions, peptide blocks HIV infection at multiple points along the way
Human defensins, aptly named antimicrobial peptides, are made in immune system cells and epithelial cells (such as skin cells and cells that line the gut). One of these peptides, human neutrophil peptide 1, under certain ...
HIV & AIDS
Jul 24, 2012 |
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Heart medication converts cancer cells into vaccine
(HealthDay) -- A class of heart medications, cardiac glycosides, can induce immunogenic cell death (ICD), whereby dying cancer cells are converted into a vaccine that stimulates antitumor response, according ...
Cancer
Jul 23, 2012 |
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Immune drug helps patients with serious kidney disorder
A drug commonly used to treat immune disorders such as lymphoma and arthritis also benefits patients with an immune disorder of the kidneys that can lead to kidney failure, according to a study appearing in an upcoming issue ...
Diseases, Conditions, Syndromes
Jul 19, 2012 |
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Driving developing brain neurons in the right direction
One of the marvels of brain development is the mass migration of nerve cells to their functional position. European research has investigated the molecules required for their successful navigation.
Neuroscience
Jul 16, 2012 |
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Can you hear me now? New strategy discovered to prevent hearing loss
If you're concerned about losing your hearing because of noise exposure (earbud deafness syndrome), a new discovery published online in the FASEB Journal offers some hope. That's because scientists from Germany and Canada ...
Medical research
Jul 06, 2012 |
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Unexpected discovery highlights new role for cell death regulator
An unexpected discovery of how the body controls cell death has revealed a potential new therapeutic target.
Medical research
Jun 14, 2012 |
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Fighting cancer with the immune system
The human immune system has a natural ability to identify and attack tumor cells. Natural killer (NK) cells are innate immune cells that are particularly effective at killing tumor cells due to their ability to secrete cytotoxic ...
Cancer
Jun 11, 2012 |
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