A new study is giving researchers hope that novel targeted therapies can be developed for glioblastoma multiforme (GBM), the most common and most aggressive form of brain cancer, after demonstrating for the first time that ...
Jan 9, 2014
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The retinoblastoma (Rb) protein plays a critical role in suppressing the multi-step process of cell migration through the bloodstream, lymphovascular invasion and the metastasis of an aggressive type of breast cancer to the ...
Dec 4, 2013
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All organisms begin life as a microscopic cluster of cells. What happens next, as they develop, is a source of endless fascination for scientists.
Dec 4, 2013
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Understanding how and why cancer cells move away from their original location is important to find ways to stop the spread of the disease. New findings, published in the Nature journal Oncogene, reveal how a protein, called ...
Nov 18, 2013
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(Medical Xpress)—A cellular pathway interaction known as TWEAK-Fn14, often associated with repair of acute injuries, also is a viable target for drug therapy that could prevent the spread of cancer, especially brain cancer, ...
Nov 8, 2013
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A crucial component of wound healing in many animals, including humans, is the migration of nearby skin cells toward the center of the wound. These cells fill the wound in and help prevent infection while new skin cells regenerate.
Oct 29, 2013
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If the development of our nervous system is disturbed, we risk developing serious neurological diseases, impairing our sensory systems, movement control or cognitive functions. This is true for all organisms with a well-developed ...
Sep 19, 2013
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A team led by scientists from The Scripps Research Institute (TSRI) have shown that a protein once thought to inhibit the growth of tumors is instead required for initial tumor growth. The findings could point to a new approach ...
Sep 4, 2013
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The invasion of brain-tumor cells into surrounding tissue requires the same protein molecule that neurons need to migrate into position as they differentiate and mature, according to new research from the University of Illinois ...
Aug 7, 2013
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Scientists at The Scripps Research Institute (TSRI) have decoded an important molecular signal that guides the development of a key region of the brain known as the neocortex. The largest and most recently evolved region ...
Aug 7, 2013
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