Neuroscience

Autism gene stunts neurons, but growth can be restored, in mice

Brown University researchers have traced a genetic deficiency implicated in autism in humans to specific molecular and cellular consequences that cause clear deficits in mice in how well neurons can grow the intricate branches ...

Diseases, Conditions, Syndromes

RNA processing and antiviral immunity

The RIG-I like receptors (RLRs) are intracellular enzyme sentries that detect viral infection and initiate a first line of antiviral defense. The cellular molecules that activate RLRs in vivo are not clear.

Oncology & Cancer

Research team discovers new target for CAR T cells in solid tumors

Chimeric antigen receptor T-cell therapy, or CAR T, has made a big impact on the treatment of certain blood cancers, allowing patients with relapsed/refractory disease to live longer, healthier lives. But in clinical study, ...

Diseases, Conditions, Syndromes

Rogue receptor opens door for rare kidney disease

Effects of a particularly devastating human kidney disease may be blunted by making a certain cellular protein receptor much less receptive, according to new research by scientists from North Carolina State University and ...

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