Engineered T cells kill tumors but spare normal tissue in an animal model
The need to distinguish between normal cells and tumor cells is a feature that has been long sought for most types of cancer drugs. Tumor antigens, unique proteins on the surface of a tumor, are potential targets for a normal ...
Cancer
Apr 07, 2013 |
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Accelerated biological aging, seen in women with Alzheimer's risk factor, blocked by hormone therapy
Healthy menopausal women carrying a well-known genetic risk factor for Alzheimer's disease showed measurable signs of accelerated biological aging, a new study has found.
Alzheimer's disease & dementia
Feb 13, 2013 |
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Synthetic 'poop' can cure C. difficile infection, study finds
A synthetic "poop" developed at the University of Guelph can cure nasty gastrointestinal infections caused by Clostridium difficile, a toxin-producing bacterium.
Diseases, Conditions, Syndromes
Jan 08, 2013 |
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Ibrutinib has 'unprecedented' impact on mantle cell lymphoma
An international study of ibrutinib in people with relapsed or refractory mantle cell lymphoma (MCL) continues to show unprecedented and durable results with few side effects.
Cancer
Dec 14, 2012 |
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Pre-transplant umbilical cord blood expansion speeds establishment of new blood supply in patients
Donated umbilical cord blood establishes a new blood supply in patients more quickly after transplantation when it is first expanded in the lab on a bed of cells that mimics conditions in the bone marrow, researchers report ...
Medical research
Dec 12, 2012 |
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Previously unknown mechanism identified in oncogene-induced senescence
Cell aging, or cellular senescence, has an important role in the natural physiological response to tumor development. Activated oncogenes are able to induce senescence, and recent findings have suggested that oncogene-induced ...
Cancer
Dec 12, 2012 |
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Study reveals insights that could aid in therapeutic use of mesenchymal stem cells
Mesenchymal stem cells (MSCs), are a newly emerging cellular therapy being tested in approximately 250 clinical trials worldwide to help repair damaged tissues, such as injured heart muscle following a heart attack. The problem ...
Medical research
Nov 15, 2012 |
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Scientists identify new target for lung cancer treatment
A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed ...
Cancer
Nov 01, 2012 |
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Research could lead to new ways to ID women who have higher risk of breast cancer from low-dose radiation
(Medical Xpress)—Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have identified tissue mechanisms that may influence a woman's susceptibility or resistance ...
Cancer
Oct 16, 2012 |
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Neonatal heart stem cells may help mend kids' broken hearts
Researchers at the University of Maryland School of Medicine, who are exploring novel ways to treat serious heart problems in children, have conducted the first direct comparison of the regenerative abilities of neonatal ...
Cardiology
Sep 10, 2012 |
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Tapping the body to fight disease
Biju Parekkadan saw his future in the plight of a newborn thousands of miles away.
Medical research
Sep 03, 2012 |
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Gene therapy restores sense of smell, may aid research into other diseases caused by cilia defects
Scientists have restored the sense of smell in mice through gene therapy for the first time—a hopeful sign for people who can't smell anything from birth or lose it due to disease.
Medical research
Sep 02, 2012 |
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Improved image analysis for MRI
Reliable, accurate and repeatable analysis of medical images continues to be a challenge in disease treatment. A European research initiative has developed robust and efficient computing techniques for image ...
Medical research
Jul 16, 2012 |
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Cells derived from debrided burn tissue may be useful for tissue engineering
A research team in the Netherlands has found that cells from burn eschar, the non-viable tissue remaining after burn injury and normally removed to prevent infection, can be a source of mesenchymal cells that may be used ...
Medical research
Jul 11, 2012 |
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Newly identified protein function protects cells during injury
Scientists have discovered a new function for a protein that protects cells during injury and could eventually translate into treatment for conditions ranging from cardiovascular disease to Alzheimer's.
Medical research
Jun 07, 2012 |
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