Alzheimer's disease & dementia

New biomarker for Alzheimer's disease found via CRISPR technique

The objective of the research, undertaken in the laboratories of the IBPM, is to develop a model for studying Alzheimer's disease (AD) of sporadic origin—in other words, AD that is not due to a hereditary genetic mutation. ...

Medical research

New research sheds light 'gender gap' in cystic fibrosis

A minor hiccup in the sequence of a human gene can have devastating impacts on health. Such flaws cause cystic fibrosis (CF), a disease affecting the lungs and other vital organs, often leading to death by the age of 30.

Medical research

Observing brain diseases in real time

An innovative tool allows researchers to observe protein aggregation throughout the life of a worm. The development of these aggregates, which play a role in the onset of a number of neurodegenerative diseases, can now be ...

Neuroscience

Scientists develop ataxia mouse model

Scientists at the Ruhr-Universität Bochum established a mouse model for the human disease SCA6. SCA6 is characterised by movement deficits and caused by similar genetic alterations as Chorea Huntington. The mouse model will ...

Medical research

Hunting the ion channel

The electrical impulse that powers the workings of the brain and the heart begins with charged particles passing through cellular structures known as ion channels. Using the same technique used to decode the structure of ...

Medical research

Researchers uncover a new role of 'moonlighting' proteins

Although known to regulate fundamental cellular processes in humans, including cell growth, division and programmed cell death, the protein group known as chloride intracellular channel (CLIC) proteins is yet to be fully ...

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