Medical research

BPA may affect the developing brain by disrupting gene regulation

Environmental exposure to bisphenol A (BPA), a widespread chemical found in plastics and resins, may suppress a gene vital to nerve cell function and to the development of the central nervous system, according to a study ...

Neuroscience

How synaptic vesicles accumulate glutamate

In the brain, neurons communicate via neurotransmitters, which trigger electrical signals in downstream neurons by binding and activating specific receptors. Neurotransmitters are released through the fusion of synaptic vesicles, ...

Medical research

Protein linked to intellectual disability has complex role

Fragile X syndrome, the leading inherited cause of intellectual disability, is due to a genetic mutation that largely eliminates the fragile X protein, a critical element of normal brain development and function.

Genetics

The surprising twist behind a rare neurological disorder

A fruit fly study, by an international group of researchers, has pinpointed how a genetic mutation causes one of the important molecular machines in our cells to malfunction. The findings provide a biological mechanism behind ...

Medical research

Transporter imbalance implicated in schizophrenia

Alterations in the balance of two chloride ion transporters may be responsible for cognitive deficits in schizophrenia, according to a Northwestern Medicine study published in Science Advances.

Neuroscience

Scientists turn unexpected brain study results into research tool

Puzzled by their experimental results, a team of scientists from Baylor College of Medicine and Texas Children's Hospital investigated why a research tool that was expected to suppress neuronal activity actually was stimulating ...

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