Scientists investigating the interactions, or binding patterns, of a major tumor-suppressor protein known as p53 with the entire genome in normal human cells have turned up key differences from those observed in cancer cells. ...
Nov 30, 2011
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On average, the human body contains 35 trillion red blood cells (RBCs). Approximately three million of these small disc-shaped cells die in one second. But in this second, the same number is also produced to maintain the ...
May 20, 2020
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BGI, the world's largest genomics organization, Peking University Shenzhen Hospital and Shenzhen Second People's Hospital, announced today that the study on frequent mutations of chromatin remodeling genes in transitional ...
Aug 7, 2011
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In an article published online this week in Nature Genetics, a University of Colorado Cancer Center team in partnership with universities in China and Denmark reports the first genetic sequencing of urothelial (transitional) ...
Aug 11, 2011
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Advancing the understanding of synovial sarcoma, a highly aggressive and rare cancer of young people, scientists at Dana-Farber Cancer Institute have discovered how an abnormal protein misdirects and disrupts the control ...
Aug 3, 2020
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Utah scientists have discovered new functions of a key cellular machine that regulates gene packaging and is mutated in 20% of human cancers. The study was published in print today in the journal Molecular Cell.
Nov 19, 2020
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The structure of chromatin—the mixture of DNA and proteins that form chromosomes—can affect gene expression, and certain chromatin "readers" are important for monitoring this structure often in response to environmental ...
Aug 22, 2022
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A pair of researchers at Emory University has found that some CpGs in the genome can be hemimethylated by design, rather than by chance. In their paper published in the journal Science, Chenhuan Xu and Victor Corces describe ...
Every cancer starts with a single cell, and Jackson Laboratory (JAX) researchers have found a precise and reliable way—whole-genome profiling of open chromatin—to identify the kind of cell that leads to a given case of ...
Jul 11, 2016
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A new study published November 20 in the open-access journal PLOS Biology has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory differences distinguish ...
Nov 20, 2012
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