Diseases, Conditions, Syndromes

High sustained response rate for glecaprevir, pibrentasvir in HCV

(HealthDay)—For patients with stage 4 or 5 chronic kidney disease and hepatitis C virus (HCV) infection, 12 weeks of treatment with glecaprevir and pibrentasvir results in a high rate of sustained virologic response, according ...

Diseases, Conditions, Syndromes

Newer tests could cut hep C diagnosis steps in half

Data suggest that several commercially available tests for hepatitis C virus core antigen (HCVcAg) are highly sensitive and specific and could transform the current two-test screening process for HCV into a single test. A ...

Diseases, Conditions, Syndromes

Rare disease gene has a key role in chronic hepatitis C infection

Hepatitis C virus (HCV) hijacks the host's fat metabolism for its own survival, growth, and transport in the human body. A study published on April 28th in PLOS Pathogens identifies a host gene involved in the formation of ...

Diseases, Conditions, Syndromes

Hepatitis C virus uses Netrin-1 to hijack host cells

Hepatitis C virus (HCV) is a small, enveloped virus comprising an RNA genome encased in a protein capsid and surrounded by a lipid bilayer containing two glycoproteins. Acute infection can cause hepatitis but the virus usually ...

Diseases, Conditions, Syndromes

Total medical costs of $16K for IFN-based antiviral tx for HCV

(HealthDay)—The total medical costs associated with interferon (IFN)-based antiviral treatment among patients with chronic hepatitis C virus (HCV) infection average €14,559, with a mean cost of €38,514 per sustained ...

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