Survival gene may be key to controlling HIV and hepatitis
(Medical Xpress)—A newly discovered gene that is essential for embryo survival could also hold the key to treating and potentially controlling chronic infections such as HIV, hepatitis and tuberculosis.
Immunology
Nov 26, 2012 |
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Good bugs gone bad: Gut immune cells keep beneficial microbes in their place
The healthy human intestine is colonized with over 100 trillion beneficial, or commensal, bacteria of many different species. In healthy people, these bacteria are limited to the intestinal tissues and have ...
Medical research
Jun 06, 2012 |
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Discovery provides blueprint for new drugs that can inhibit hepatitis C virus
Chemists at the University of California, San Diego have produced the first high resolution structure of a molecule that when attached to the genetic material of the hepatitis C virus prevents it from reproducing.
Medical research
Mar 19, 2012 |
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First trial of a new hepatitis C vaccine shows promise
(Medical Xpress) -- A new vaccine against the chronic liver disease hepatitis C has shown promising results in a first clinical trial in humans, Oxford University researchers report.
Diseases, Conditions, Syndromes
Jan 05, 2012 |
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Study reveals new mechanism for estrogen suppression of liver lipid synthesis
By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases.
Medical research
May 23, 2013 |
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Sunshine hormone, vitamin D, may offer hope for treating liver fibrosis
Liver fibrosis results from an excessive accumulation of tough, fibrous scar tissue and occurs in most types of chronic liver diseases. In industrialized countries, the main causes of liver injury leading ...
Medical research
Apr 25, 2013 |
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Sofosbuvir shows promise for chronic hepatitis C infection
(HealthDay)—Sofosbuvir seems to be a promising treatment option for patients with chronic hepatitis C virus (HCV) infection, according to two studies published online April 23 in the New England Journal of ...
Diseases, Conditions, Syndromes
Apr 23, 2013 |
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Potential therapy for HIV suggested: Blocking key protein boosts body's ability to clear chronic infection
UCLA scientists have shown that temporarily blocking a protein critical to immune response actually helps the body clear itself of chronic infection. Published in the April 12 edition of Science, the findin ...
HIV & AIDS
Apr 11, 2013 |
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Team discovers new gene that affects clearance of hepatitis C virus
(Medical Xpress)—Scientists have discovered a gene that interferes with the clearance of hepatitis C virus infection. They also identified an inherited variant within this gene, Interferon Lambda 4 (IFNL4), that predicts ...
Genetics
Jan 08, 2013 |
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Sustained virological response linked with improved survival for patients with chronic HCV infection
Among patients with chronic hepatitis C virus infection and advanced hepatic fibrosis (development of excess fibrous connective tissue), sustained virological response (SVR) to interferon-based treatment was associated with ...
Diseases, Conditions, Syndromes
Dec 25, 2012 |
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Researchers discover how hepatitis C virus reprograms human liver cells
Hepatitis C virus has evolved to invade and hijack the basic machinery of the human liver cell to ensure its survival and spread. Researchers at the University of North have discovered how hepatitis C binds ...
Diseases, Conditions, Syndromes
Dec 18, 2012 |
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Molecular root of 'exhausted' T cells in chronic viral infection
When you get an acute infection, such as influenza, the body generally responds with a coordinated response of immune-cell proliferation and attack that rapidly clears the pathogen. Then, their mission done, the immune system ...
Medical research
Nov 29, 2012 |
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Blocking tumor-induced inflammation impacts cancer development
Researchers at the University of California, San Diego School of Medicine report the discovery of microbial–dependent mechanisms through which some cancers mount an inflammatory response that fuels their ...
Cancer
Oct 03, 2012 |
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Molecular and protein markers discovered for liver transplant failure from hepatitis C
Researchers have discovered molecular and protein signatures that predict rapid onset of liver damage in hepatitis C patients following a liver transplant. The markers appeared soon after transplant and well before clinical ...
Diseases, Conditions, Syndromes
Aug 16, 2012 |
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Immune responses can be generated locally within human melanoma skin metastases
In many types of cancer, activated immune cells infiltrate the tumor and influence clinical outcome. It is not always clear where these cells are activated, but results reported in Cancer Research, a journal of the Americ ...
Cancer
Jul 31, 2012 |
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