News tagged with critical protein


Study finds immunity protein that ramps up inflammation, and agents that can block it

Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival ...

Immunology created Mar 31, 2013 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast

Recipe for large numbers of stem cells requires only one ingredient

Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the ...

Medical research created Apr 17, 2013 | popularity 5 / 5 (6) | comments 1 | with audio podcast

Research advances therapy to protect against dengue virus

Nearly half of the world's population is at risk of infection by the dengue virus, yet there is no specific treatment for the disease. Now a therapy to protect people from the virus could finally be a step ...

Diseases, Conditions, Syndromes created Apr 08, 2013 | popularity not rated yet | comments 0 | with audio podcast

Hope in stopping melanoma from spreading: Study shows that inhibiting key protein prevents metastasis to lungs in mice

(Medical Xpress)—Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer. Inhibition of the protein known as adenosine diphosphate ribosylation ...

Cancer created Mar 05, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New findings on heat shock proteins may shed light on variety of debilitating diseases

UCLA researchers, in a finding that runs counter to conventional wisdom, have discovered for the first time that a gene thought to express a protein in all cells that come under stress is instead expressed only in specific ...

Medical research created Jan 29, 2013 | popularity not rated yet | comments 0 | with audio podcast

Scientists uncover potential drug target to block cell death in Parkinson's disease

Oxidative stress is a primary villain in a host of diseases that range from cancer and heart failure to Alzheimer's disease, Amyotrophic Lateral Sclerosis and Parkinson's disease. Now, scientists from the Florida campus of ...

Parkinson's & Movement disorders created Jan 10, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

MECP2 duplication affects immune system as well as brain development

In 1999, Dr. Huda Zoghbi and colleagues at Baylor College of Medicine identified the genetic cause of Rett syndrome (a neurological disorder that begins after birth) – MECP2 mutation. Too little of the MeCP2 protein associated ...

Medical research created Dec 05, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists reveal how deadly Marburg virus silences immune system

Scientists at The Scripps Research Institute have determined the structure of a critical protein from the Marburg virus, a close cousin of Ebola virus. These viruses cause similar diseases and are some of ...

Medical research created Sep 13, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

New study represents major breakthrough in macular degeneration

University of Kentucky researchers, led by Dr. Jayakrishna Ambati, have made an exciting finding in the "dry" form of age-related macular degeneration known as geographic atrophy (GA). GA is an untreatable condition that ...

Medical research created Aug 06, 2012 | popularity 4.8 / 5 (6) | comments 0 | with audio podcast

Researchers, with stem cells, advance understanding of spinal muscular atrophy

Cedars-Sinai's Regenerative Medicine Institute has pioneered research on how motor-neuron cell-death occurs in patients with spinal muscular atrophy, offering an important clue in identifying potential medicines to treat ...

Medical research created Jun 20, 2012 | popularity not rated yet | comments 0 | with audio podcast

Etanercept - genetically engineered compound for back pain - falls short: study

Despite the great promise that injecting a new type of anti-inflammatory pain medicine into the spine could relieve the severe leg and lower back pain of sciatica, a Johns Hopkins-led study has found that the current standard ...

Medical research created Apr 16, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

The USP15 biological thermostat: A promising novel therapeutic target in cancer

After years studying the molecular bases of glioblastoma - the most common brain tumor and one of the most aggressive of all cancers, the group led by Dr. Joan Seoane , Director of Translational Research at the Vall d'Hebron ...

Cancer created Feb 19, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study reveals enzyme function, could help find muscular dystrophy therapies

Researchers at the University of Iowa have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings, which were published Jan. 6 ...

Medical research created Jan 09, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Research links telomere length to emphysema risk

Telomeres, the body's own cellular clocks, may be a crucial factor underlying the development of emphysema, according to research from Johns Hopkins University.

Medical research created Jul 15, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Genetic disease linked to protein build-up

Mutations of the gene Lmna previously thought to be directly responsible for a group of laminopathies—serious developmental conditions including premature aging and a form of muscular dystrophy—in fact ...

Medical research created Aug 29, 2012 | popularity not rated yet | comments 0