Large-scale genetic study defines relationship between primary sclerosing cholangitis and other autoimmune diseases
For the first time, scientists show that a leading cause of liver transplant, primary sclerosing cholangitis (PSC), is a distinct disease from inflammatory bowel disease, opening up new avenues for specific PSC treatments.
Genetics
Apr 21, 2013 |
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Itching for new help for eczema: Recently identified immune cells possible therapeutic target
Researchers have identified a previously unknown critical role for a recently identified immune cell population in the progression of atopic dermatitis. The team found an accumulation of innate lymphoid cells ...
Immunology
Jan 30, 2013 |
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Transmission of tangles in Alzheimer's mice provides more authentic model of tau pathology
Brain diseases associated with the misformed protein tau, including Alzheimer's disease and frontotemporal lobar degeneration with tau pathologies, are characterized by neurofibrillary tangles (NFTs) comprised ...
Neuroscience
Jan 15, 2013 |
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Parkinson's disease protein causes disease spread and neuron death in healthy animals
Understanding how any disease progresses is one of the first and most important steps towards finding treatments to stop it. This has been the case for such brain-degenerating conditions as Alzheimer's disease. ...
Parkinson's & Movement disorders
Nov 15, 2012 |
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Discovery may shed light on why some HIV-positive patients have more virus
(Medical Xpress)—Biologists at UC San Diego have unraveled the anti-viral mechanism of a human gene that may explain why some people infected with HIV have much higher amounts of virus in their bloodstreams ...
HIV & AIDS
Sep 24, 2012 |
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Two proteins offer a 'clearer' way to treat Huntington's disease
In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critic ...
Neuroscience
Jul 11, 2012 |
4.8 / 5 (4) |
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Using patients' own tumor-fighting cells to knock back advanced melanoma
A small, early-phase clinical trial to test the effectiveness of treating patients with advanced melanoma using billions of clones of their own tumor-fighting cells combined with a specific type of chemotherapy has shown ...
Cancer
Mar 05, 2012 |
4.8 / 5 (5) |
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Scientists solve mystery of nerve disease genes
For several years, scientists have been pondering a question about a genetic disease called Charcot-Marie-Tooth (CMT) disease type 2D: how can different types of mutations, spread out across a gene, produce ...
Medical research
Jul 04, 2011 |
4.3 / 5 (3) |
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Scientists develop drug that slows Alzheimer's in mice
A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment. The findings, ...
Alzheimer's disease & dementia
May 13, 2013 |
4.2 / 5 (5) |
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Ingredient in new MS drug linked to serious brain disease
(HealthDay)—The active ingredient in a drug that's expected to become a popular treatment for multiple sclerosis has been linked to four European cases of a rare but sometimes fatal brain disease called ...
Medications
Apr 24, 2013 |
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Study uncovers key factor in Alzheimer's progression
(Medical Xpress)—A new study from researchers at the University of Florida may have uncovered a critical factor that drives the relentless progression of Alzheimer's disease ― a discovery that could eventually slow its ...
Alzheimer's disease & dementia
Apr 16, 2013 |
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Potential therapy for HIV suggested: Blocking key protein boosts body's ability to clear chronic infection
UCLA scientists have shown that temporarily blocking a protein critical to immune response actually helps the body clear itself of chronic infection. Published in the April 12 edition of Science, the findin ...
HIV & AIDS
Apr 11, 2013 |
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Unusual suspect: Scientists find 'second fiddle' protein's role in Type 2 diabetes
A team of researchers at the Johns Hopkins Children's Center has found that a protein long believed to have a minor role in type 2 diabetes is, in fact, a central player in the development of the condition that affects nearly ...
Diabetes
Apr 11, 2013 |
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Study shines light on how stress circuits learn
Researchers at the University of Calgary's Hotchkiss Brain Institute have discovered that stress circuits in the brain undergo profound learning early in life. Using a number of cutting edge approaches, including ...
Neuroscience
Apr 07, 2013 |
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Newly identified tumor suppressor provides therapeutic target for prostate cancer
Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have identified how an enzyme called PKCζ suppresses prostate tumor formation. The finding, which also describes a molecular chain ...
Cancer
Apr 01, 2013 |
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