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Patenting the human genome

Can human genes be patented? That was the question posed by Alan J. Snyder, vice president and associate provost for research and graduate studies at Lehigh, and Lee Kaplan, scientific director of cellular and molecular genetics ...

Genetics created May 24, 2013 | popularity 4 / 5 (1) | comments 0

Mayo Clinic genomic analysis lends insight to prostate cancer

Mayo Clinic researchers have used next generation genomic analysis to determine that some of the more aggressive prostate cancer tumors have similar genetic origins, which may help in predicting cancer progression. The findings ...

Cancer created May 23, 2013 | popularity not rated yet | comments 0

How healthy are you for your age?

On May 22, JoVE will publish details of a technique to measure the health of human genetic material in relation to a patient's age. The method is demonstrated by the laboratory of Dr. Gil Atzmon at New York's Albert Einste ...

Medical research created May 22, 2013 | popularity 5 / 5 (1) | comments 0

A molecular explanation for age-related fertility decline in women

(Medical Xpress)—Scientists supported by the National Institutes of Health have a new theory as to why a woman's fertility declines after her mid-30s. They also suggest an approach that might help slow ...

Medical research created May 22, 2013 | popularity not rated yet | comments 0 | with audio podcast

Novel RNA-based classification system for colorectal cancer

A novel transcriptome-based classification of colon cancer that improves the current disease stratification based on clinicopathological variables and common DNA markers is presented in a study published in PLOS Medicine this w ...

Cancer created May 21, 2013 | popularity not rated yet | comments 0

Genetic predictors of postpartum depression uncovered

Johns Hopkins researchers say they have discovered specific chemical alterations in two genes that, when present during pregnancy, reliably predict whether a woman will develop postpartum depression.

Psychology & Psychiatry created May 21, 2013 | popularity not rated yet | comments 0 | with audio podcast

Experts urge caution over use of new genetic sequencing techniques

The use of genome-wide analysis (GWA), where the entirety of an individual's DNA is examined to look for the genomic mutations or variants which can cause health problems is a massively useful technology for diagnosing disease. ...

Genetics created May 16, 2013 | popularity not rated yet | comments 0

Collecting DNA for human rights: How to help while safeguarding privacy

DNA databases might help identify victims of crime and human trafficking, but how do we safeguard the personal privacy of innocent victims and family members? A new report online May 15 in the Cell Press journal Trends in ...

Genetics created May 15, 2013 | popularity not rated yet | comments 0

What is BRCA1?

Actress Angelina Jolie has today written an op-ed in the New York Times explaining that she has opted to have a double mastectomy because she carries the hereditary BRCA1 gene, which she says increases her risk o ...

Cancer created May 15, 2013 | popularity 5 / 5 (1) | comments 2

Evidence of host adaptation of avian-origin influenza A virus

The connection between human avian-origin influenza A (H7N9) virus infection and environmental sources of the virus were determined based on clinical data, epidemiology, and virological characteristics of the three early ...

Diseases, Conditions, Syndromes created May 15, 2013 | popularity 5 / 5 (1) | comments 0

Study IDs key protein for cell death, offers way to kill cancer cells by forcing them into programmed-death pathway

When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ...

Genetics created May 14, 2013 | popularity 5 / 5 (9) | comments 0 | with audio podcast

Gene mutation as cause of breast and ovarian cancer

A change to the so-called TERT gene considerably increases the risk of breast and ovarian cancer. This is the result of a current, multicenter study in which the University Department of Gynaecology and the ...

Cancer created May 10, 2013 | popularity not rated yet | comments 0

Scientists confirm Justinianic Plague caused by bacterium Yersinia pestis

(Medical Xpress)—From the several pandemics generally called 'pestilences' three are historically recognized as due to plague, but only for the third pandemic of the 19th-21st centuries AD there were microbiological ...

Diseases, Conditions, Syndromes created May 10, 2013 | popularity not rated yet | comments 0 | with audio podcast

Mapping the embryonic epigenome

A large, multi-institutional research team involved in the NIH Epigenome Roadmap Project has published a sweeping analysis in the current issue of the journal Cell of how genes are turned on and off to direct early human ...

Genetics created May 09, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Research reveals cancer-suppressing protein 'multitasks'

The understanding of how a powerful protein called p53 protects against cancer development has been upended by a discovery by Walter and Eliza Hall Institute researchers.

Cancer created May 09, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

DNA

Deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic instructions used in the development and functioning of all known living organisms and some viruses. The main role of DNA molecules is the long-term storage of information. DNA is often compared to a set of blueprints or a recipe, or a code, since it contains the instructions needed to construct other components of cells, such as proteins and RNA molecules. The DNA segments that carry this genetic information are called genes, but other DNA sequences have structural purposes, or are involved in regulating the use of this genetic information.

Chemically, DNA consists of two long polymers of simple units called nucleotides, with backbones made of sugars and phosphate groups joined by ester bonds. These two strands run in opposite directions to each other and are therefore anti-parallel. Attached to each sugar is one of four types of molecules called bases. It is the sequence of these four bases along the backbone that encodes information. This information is read using the genetic code, which specifies the sequence of the amino acids within proteins. The code is read by copying stretches of DNA into the related nucleic acid RNA, in a process called transcription.

Within cells, DNA is organized into X-shaped structures called chromosomes. These chromosomes are duplicated before cells divide, in a process called DNA replication. Eukaryotic organisms (animals, plants, fungi, and protists) store most of their DNA inside the cell nucleus and some of their DNA in the mitochondria (animals and plants) and chloroplasts (plants only). Prokaryotes (bacteria and archaea) however, store their DNA in the cell's cytoplasm. Within the chromosomes, chromatin proteins such as histones compact and organize DNA. These compact structures guide the interactions between DNA and other proteins, helping control which parts of the DNA are transcribed.

For more information about DNA, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: genes , protein , cells , genome , chromosomes