Attempting to make dopamine-producing neurons out of glial cells in mouse brains, a group of researchers instead converted mature inhibitory neurons into dopaminergic cells. Their findings, appearing October 11 in the journal ...
Oct 11, 2018
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347
As many as seven to 10 million people in the world are thought to live with Parkinson's disease (PD). Being the second most common neurodegenerative disease, PD severely affects patients' quality of life, not just brining ...
Jan 9, 2020
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95
Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.
Dec 13, 2021
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118
Currently, there are no disease modifying therapies for Parkinson's disease that can change the progression of the disease. An international team of scientists led by faculty at the University of Colorado Anschutz Medical ...
Jun 30, 2022
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77
Researchers at Karolinska Institutet in Sweden and the University of North Carolina in the USA have mapped out the cell types behind various brain disorders. The findings are published in Nature Genetics and offer a roadmap ...
Apr 27, 2020
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294
Over the past decades, many neuroscientists have investigated how the mammalian brain modulates pain, trying to uncover the neural mechanisms underpinning chronic pain. Chronic pain is pain in specific parts of the body, ...
Parkinson's is a neurodegenerative disease where dopaminergic neurons progressively die in the brainstem. Tremor and difficulties walking are recognizable movement symptoms for many people suffering from Parkinson's. Over ...
Feb 18, 2022
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116
As Parkinson's disease progresses in patients, a puzzling dichotomy plays out in their brains. One set of neurons degenerates, while a similar population nearby is spared the same degree of damage. Why the difference? An ...
Aug 10, 2015
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174
Neonatal exposure to nicotine alters the reward circuity in the brains of newborn mice, increasing their preference for the drug in later adulthood, report researchers at University of California San Diego School of Medicine ...
May 22, 2019
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1084
Scientists at the University of Virginia School of Medicine have identified a potential explanation for the mysterious death of specific brain cells seen in Alzheimer's, Parkinson's and other neurodegenerative diseases.
Feb 15, 2019
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