A team of researchers at Duke University has determined the structure of a key molecule that can carry chemotherapy and anti-viral drugs into cells, which could help to create more effective drugs with fewer effects to healthy ...
Mar 11, 2012
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(Medical Xpress) -- The multidrug transporter EmrE functions as an asymmetric antiparallel dimer (molecule with two subunits). Drug (blue) transport from the inside to the outside of the cell membrane is accomplished by exchange ...
Jan 31, 2012
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University of Iowa researchers and colleagues have discovered how malaria manipulates the immune system to allow the parasite to persist in the bloodstream. By rescuing this immune system pathway, the research team was able ...
Dec 12, 2011
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An attentive, nurturing mother may be able to help her children better resist the temptations of drug use later in life, according to a study in rats conducted by Duke University and the University of Adelaide in Australia.
Dec 6, 2011
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Dana-Farber Cancer Institute scientists have successfully disrupted the function of a cancer gene involved in the formation of most human tumors by tampering with the gene's "on" switch and growth signals, rather than targeting ...
Sep 9, 2011
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Researchers have identified a protein that, when targeted, enables cisplatin-resistant cancer cells to become responsive to treatment. Cisplatin, and other similar platinum drugs, are incredibly effective at killing rapidly ...
Mar 27, 2024
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Traditionally, therapies combining DNA-damaging agents and STING agonists have shown potential in treating cancer by enhancing immune response and reshaping the tumor microenvironment. However, until now, creating a single ...
Mar 20, 2024
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Scientists have discovered a way to stop active cancer cells in their tracks—meaning they can then be eliminated by new drug treatments.
Feb 28, 2024
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The intricate relationship that exists between humans and the gut microbiome has become a hot research topic, and scientists are constantly uncovering new reasons why a healthy diet can lead to a healthier life.
Feb 1, 2024
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Combining a pair of experimental drugs may help treat malignant peripheral nerve sheath tumors with fewer harmful side effects, according to preliminary animal studies led by investigators at the Johns Hopkins Kimmel Cancer ...
Nov 30, 2023
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