News tagged with drug resistance
Related topics: antibiotics , cancer cells , breast cancer , hiv , malaria
Drug resistance
Drug resistance is the reduction in effectiveness of a drug in curing a disease or improving a patient's symptoms. When the drug is not intended to kill or inhibit a pathogen, then the term is equivalent to dosage failure or drug tolerance. More commonly, the term is used in the context of diseases caused by pathogens.
Pathogens are said to be drug-resistant when drugs meant to neutralize them have reduced effect. When an organism is resistant to more than one drug, it is said to be multidrug resistant.
Drug resistance is an example of evolution in microorganisms. Individuals that are not susceptible to the drug effects are capable of surviving drug treatment, and therefore have greater fitness than susceptible individuals. By the process of natural selection, drug resistant traits are selected for in subsequent offspring, resulting in a population that is drug resistant.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
Glaxo, US partnering to develop new antibiotics
GlaxoSmithKline PLC says it's starting an unusual collaboration with the U.S. government to develop several antibiotics for both bioterrorism threats and bacterial infections resistant to current medicines.
Medications
May 22, 2013 |
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Researchers describe how breast cancer cells acquire drug resistance
A seven-year quest to understand how breast cancer cells resist treatment with the targeted therapy lapatinib has revealed a previously unknown molecular network that regulates cell death. The discovery provides new avenues ...
Cancer
May 07, 2013 |
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Genome sequencing provides unprecedented insight into causes of pneumococcal disease
A new study led by researchers from Harvard School of Public Health (HSPH) and the Wellcome Trust Sanger Institute in the UK has, for the first time, used genome sequencing technology to track the changes in a bacterial population ...
Genetics
May 05, 2013 |
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Scientists develop simple blood test to track tumour evolution in cancer patients
By tracking changes in patients' blood, Cambridge scientists have created a new way of looking at how tumours evolve in real-time and develop drug resistance. The research was published in the print edition ...
Cancer
May 03, 2013 |
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Gene clues point to Cambodia for resistant malaria
Gene analysis of malaria parasites has pinpointed western Cambodia as the hotspot of strains that are dangerously resistant to artesiminin, the frontline drug against the disease, scientists said on Sunday.
Genetics
Apr 28, 2013 |
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Will green tea help you lose weight?
Evidence has shown that green tea extract may be an effective herbal remedy useful for weight control and helping to regulate glucose in type 2 diabetes. In order to ascertain whether green tea truly has this potential, Jae-Hyung ...
Overweight and Obesity
Apr 29, 2013 |
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Computer program identifies rare mutations harbored within diverse populations of cancer cells and microorganisms
A tumor is not a uniform mass of identical cells. However, teasing apart genetic heterogeneity within a biopsied tumor can be difficult. Researchers often fail to tell the difference between a rare variant ...
Cancer
Apr 24, 2013 |
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Researchers make significant step forward in combating antibiotic resistance
The research led by Durham University, which involved colleagues at the University of Birmingham, is a significant development in combating antibiotic resistance; it will pave the way for the creation of the inhibitors to ...
Medical research
Apr 24, 2013 |
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Nanomal smartphone-like malaria detection device to be field tested one year earlier than scheduled
A pioneering mobile device using cutting-edge nanotechnology to rapidly detect malaria infection and drug resistance will be ready for field testing this year, one year ahead of schedule.
Diseases, Conditions, Syndromes
Apr 26, 2013 |
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