New method to find novel connections from gene to gene, drug to drug and between scientists
Researchers from Mount Sinai School of Medicine have developed a new computational method that will make it easier for scientists to identify and prioritize genes, drug targets, and strategies for repositioning drugs that ...
Medical research
Jul 24, 2012 |
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Lungs respond to hospital ventilator as if it were an infection
When hospital patients need assistance breathing and are placed on a mechanical ventilator for days at a time, their lungs react to the pressure generated by the ventilator with an out-of-control immune response that can ...
Medical research
Jul 18, 2012 |
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Scientists identify potential target for treating anhedonia - major symptom of depression
Stanford University School of Medicine scientists have laid bare a novel molecular mechanism responsible for the most important symptom of major depression: anhedonia, the loss of the ability to experience pleasure. While ...
Medical research
Jul 11, 2012 |
4.3 / 5 (6) |
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Transforming cancer treatment: Multidrug strategy emerges from new research
A Harvard researcher studying the evolution of drug resistance in cancer says that, in a few decades, “many, many cancers could be manageable.”
Cancer
Jul 11, 2012 |
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Hulk smash? Maybe not anymore: scientists block excess aggression in mice
Pathological rage can be blocked in mice, researchers have found, suggesting potential new treatments for severe aggression, a widespread trait characterized by sudden violence, explosive outbursts and hostile overreactions ...
Neuroscience
Jun 19, 2012 |
3.8 / 5 (6) |
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Investigational diabetes drug may have fewer side effects
Drugs for type 2 diabetes can contribute to weight gain, bone fractures and cardiovascular problems, but in mice, an investigational drug appears to improve insulin sensitivity without those troublesome side ...
Medical research
Jun 04, 2012 |
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Improving obesity-induced insulin sensitivity
In recent years, a growing body of evidence has linked inflammation to the development of insulin resistance. In insulin resistance, the hormone insulin is less effective in promoting glucose uptake from the bloodstream into ...
Overweight and Obesity
Jun 01, 2012 |
5 / 5 (1) |
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The right combination: Overcoming drug resistance in cancer
Overactive epidermal growth factor receptor (EGFR) signaling has been linked to the development of cancer. Several drug therapies have been developed to treat these EGFR-associated cancers; however, many patients have developed ...
Cancer
Jun 01, 2012 |
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'Jack Spratt' diabetes gene identified
Type 2 diabetes is popularly associated with obesity and a sedentary lifestyle. However, just as there are obese people without type 2 diabetes, there are lean people with the disease.
Genetics
Jun 01, 2012 |
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Whole genome sequencing of rare olfactory neuroblastoma
The Translational Genomics Research Institute (TGen) and the Virginia G. Piper Cancer Center at Scottsdale Healthcare have conducted whole genome sequencing (WGS) of a rare nasal tract cancer called olfactory neuroblastoma ...
Genetics
May 23, 2012 |
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A possible target for broad-range HPV therapeutics emerges
(Medical Xpress) -- Among viruses, human papilloma virus (HPV) stands out: with more than 180 distinct isotypes or variations catalogued to date, it presents an extremely difficult target for broad-range treatments. And while ...
Cancer
May 22, 2012 |
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Early biomarker for pancreatic cancer identified
Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have identified a new biomarker and therapeutic target for pancreatic cancer, an often-fatal disease for which there is currently ...
Cancer
May 15, 2012 |
5 / 5 (3) |
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Researchers identify potential target for anthrax drug
(Medical Xpress) -- Researchers at the University of Michigan have identified new targets for drugs that could potentially treat anthrax, the deadly infection caused by Bacillus anthracis.
Medical research
May 09, 2012 |
5 / 5 (1) |
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Advanced pancreatic tumors depend on continued oncogene activity
Researchers at Dana-Farber Cancer Institute have shown that advanced pancreatic cancers in mice can't survive without continued expression of a mutant oncogene that "rewires" key metabolic pathways to fuel the cancer cells.
Cancer
Apr 26, 2012 |
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Scientists find new breast cancer genes, rewrite rulebook
Scientists at the BC Cancer Agency and University of British Columbia have identified new breast cancer genes that could change the way the disease is diagnosed and form the basis of next-generation treatments.
Cancer
Apr 18, 2012 |
4.5 / 5 (2) |
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