Genetics

The line of succession in neuron function

A specific region of messenger RNAs, the 3' untranslated region (3'UTR), plays an important role for cells to function properly. During embryonic development, 3'UTRs in hundreds of RNAs lengthen exclusively in neurons, which ...

Neuroscience

Stem cells can repair Parkinson's-damaged circuits in mouse brains

The mature brain is infamously bad at repairing itself following damage like that caused by trauma or strokes, or from degenerative diseases like Parkinson's. Stem cells, which are endlessly adaptable, have offered the promise ...

Medical research

Uncovering the clock that sets the speed of embryo development

Why do pregnancies last longer in some species than others? Researchers at the Francis Crick Institute have found the clock that sets the speed of embryonic development and discovered the mechanism is based on how proteins ...

Medical research

Generation of three-dimensional heart organoids

Researchers from Tokyo Medical and Dental University (TMDU) use mouse embryonic stem cells to engineer three-dimensional functional heart organoids resembling the developing heart

Genetics

Genetic mutations may be linked to infertility, early menopause

A new study from Washington University School of Medicine in St. Louis identifies a specific gene's previously unknown role in fertility. When the gene is missing in fruit flies, roundworms, zebrafish and mice, the animals ...

Medical research

Persistent DNA damage in the placenta affects pregnancy outcomes

Scientists at the Stowers Institute for Medical Research have shown that a dysfunctional placenta can play a previously unrecognized role during the earliest stages of development in mouse models of Cornelia de Lange syndrome. ...

Medical research

Researchers find potential treatment for Rett Syndrome

An experimental cancer drug can extend the life of mice with Rett Syndrome, a devastating genetic disorder that afflicts about one of every 10,000 to 15,000 girls within 6 to 18 months after birth, Yale researchers report ...

page 12 from 40