News tagged with epigenetic mechanisms
Researchers discover possible trigger for spread of head and neck cancer cells
(Medical Xpress)—Very little has been known about the epigenetic events—developmental and environmental factors affecting genes—that occur prior to the invasive growth of head and neck squamous cell carcinomas and their ...
Cancer
May 08, 2013 |
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Mechanisms regulating inflammation associated with type 2 diabetes, cancer identified
A study led by researchers at Boston University School of Medicine (BUSM) has identified epigenetic mechanisms that connect a variety of diseases associated with inflammation. Utilizing molecular analyses of gene expression ...
Immunology
Mar 01, 2013 |
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Gene regulator in brain's executive hub tracked across lifespan
For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain's executive hub. Among key findings ...
Autism spectrum disorders
Feb 02, 2012 |
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Cell contents may be key to controlling toxicity of Huntington's disease protein
New research into the cell-damaging effects of Huntington's disease suggests a potentially new approach for identifying possible therapeutic targets for treating the nerve-destroying disorder.
Genetics
Jun 06, 2012 |
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Epigenetic changes shed light on biological mechanism of autism
Scientists from King's College London have identified patterns of epigenetic changes involved in autism spectrum disorder (ASD) by studying genetically identical twins who differ in autism traits. The study, published in ...
Autism spectrum disorders
Apr 23, 2013 |
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Life experiences put their stamp on the next generation: New insights from epigenetics
The 18th century natural philosopher Jean-Baptiste Lamarck proposed that the necks of giraffes lengthened as a consequence of the cumulative effort, across generations, to reach leaves just out of their grasp. This view of ...
Psychology & Psychiatry
Feb 14, 2013 |
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Replicating risk genes in bipolar disorder
One of the biggest challenges in psychiatric genetics has been to replicate findings across large studies.
Psychology & Psychiatry
Oct 15, 2012 |
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Colon cancer exhibits a corresponding epigenetic pattern in mice and humans
Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between ...
Genetics
Feb 07, 2013 |
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KDM1 may represent a new therapeutic target for glioma
Researchers have generated preclinical data demonstrating that the protein KDM1, which functions as a lysine demethylase, is a potential target for glioma treatment, according to Gangadhara R. Sareddy, Ph.D., a postdoctoral ...
Cancer
Apr 08, 2013 |
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The relationship between prenatal stress and obesity is confirmed in rats
The intrauterine environment plays an important role in the health of the offspring. Now, experts from the University of Navarra affirm that the mother's stress, due to socio-economic or psycho-social causes, is associated ...
Health
Apr 09, 2013 |
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Researchers link cancer to failures in chromosome protection for the first time
A study published today in the journal Nature Genetics explores a new mechanism that may contribute to the development of several tumours, including Chronic Lymphocytic Leukaemia, a type of cancer that affects more than a ...
Genetics
Mar 19, 2013 |
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Lab-made tissue picks up the slack of Petri dishes in cancer research
New research demonstrates that previous models used to examine cancer may not be complex enough to accurately mimic the true cancer environment. Using oral cancer cells in a three-dimensional model of lab-made tissue that ...
Cancer
Jan 11, 2012 |
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Epigenetics mechanism may help explain effects of mom's nutrition on her children's health
Pioneering studies by U. S. Department of Agriculture-funded research molecular geneticist Robert A. Waterland are helping explain how the foods that soon-to-be-moms eat in the days and weeks around the time of conception—or ...
Genetics
Mar 11, 2013 |
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Soy-based compound may reduce tumor cell proliferation in colorectal cancer
Research on a soy-based treatment for colorectal cancer, a promising agent in ovarian cancer, and a new drug target for advanced prostate cancer was presented at the American Association for Cancer Research 2013 Annual Meeting. ...
Cancer
Apr 11, 2013 |
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The molecular mechanisms behind the benefits of exercise
Leading a sedentary lifestyle increases risk of developing type 2 diabetes. European scientists focused on delineating the mechanisms responsible for the beneficial effects of exercise on our metabolism.
Other
Sep 20, 2012 |
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