In a recent study published in Science Advances, Charles E. Gast and co-workers detail the spontaneous process of cancer cell fusion with white blood cells to produce heterogenous hybrid clones in multiple biological systems, ...
Researchers at Zhejiang University School of Medicine, China, have investigated how the body's innate immune system of renal macrophages works to prevent kidney stones. In a paper, "Renal macrophages monitor and remove particles ...
The resistance to cancer treatment is often credited to the heterogenous cellular nature within a tumor. The tumor cell-cell interaction and cell-microenvironment have a key role in the invasion and progression of tumors ...
In the ongoing quest to discover which constituents of the immune system provide highly specified protection, scientists have found that a component of the innate immune system is endowed with the capability of guarding the ...
Premature rupture of the amniotic sac can have devastating consequences, but scientists in Japan are studying instances when the damaged sac repairs itself—a phenomenon that requires cooperation of the developing fetus.
To effectively combat an infection, the body first has to sense it's been invaded, then the affected tissue must send out signals to corral resources to fight the intruder. Knowing more about these early stages of pathogen ...
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A team of Duke researchers has discovered that cells lining the gut of zebrafish—and probably humans too—have a remarkable defense mechanism when faced with certain kinds of toxins: they hit the eject button.
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Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute, with colleagues in China, have developed a new, regenerative medicine approach to remove congenital cataracts in infants, permitting ...
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(Medical Xpress)—Commensal microbiota, populations of bacteria that inhabit the tissues of larger organisms, often have complex relationships with their hosts. Researchers have been aware for some time that commensal microbiota ...
(MedicalXpress)—Originating in the thymus, the autoimmune regulator (Aire) protein controls a key mechanism that prevents the immune system from attacking the body itself. Individual T cells attack different substances; ...
In biology and medicine, an epithelium is a tissue composed of cells that line the cavities and surfaces of structures throughout the body. Many glands are also formed from epithelial tissue. It lies on top of connective tissue, and the two layers are separated by a basement membrane.
In humans, epithelium is classified as a primary body tissue, the other ones being connective tissue, muscle tissue and nervous tissue.
Epithelium is often defined by the expression of the adhesion molecule e-cadherin (as opposed to n-cadherin, which is used by cells of the connective tissue).
Functions of epithelial cells include secretion, selective absorption, protection, transcellular transport and detection of sensation and they commonly as a result present extensive apical-basolateral polarity (e.g. different membrane proteins expressed) and specialisation.
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