News tagged with epithelial cells

Related topics: cells , cancer cells , protein

Understanding cell organization to tackle cancer

Scientists at The University of Manchester have identified how cells know which way up they need to be. The discovery could help in the fight against cancer because in the early stages of the disease the cells become disorganised.

Dec 23, 2012
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Landmark study describes prostate cancer metastasis switch

Prostate cancer doesn't kill in the prostate – it's only once the disease travels to bone, lung, liver, etc. that it turns fatal. Previous studies have shown that loss of the protein E-Cadherin is essential for this metastasis. ...

Apr 02, 2013
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Study helps resolve debate about how tumors spread

A team of scientists, led by researchers at the University of California, San Diego School of Medicine, has shown for the first time how cancer cells control the ON/OFF switch of a program used by developing ...

Nov 29, 2012
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MicroRNA makes triple-negative breast cancer homesick

Epithelial cells are homebodies – they like to attach to things and becoming detached initiates a form of cell suicide known as anoikis (literally "homeless" in Latin). But in order for cancer cells to metastasize they ...

Nov 21, 2012
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Epithelium

In biology and medicine, an epithelium is a tissue composed of cells that line the cavities and surfaces of structures throughout the body. Many glands are also formed from epithelial tissue. It lies on top of connective tissue, and the two layers are separated by a basement membrane.

In humans, epithelium is classified as a primary body tissue, the other ones being connective tissue, muscle tissue and nervous tissue.

Epithelium is often defined by the expression of the adhesion molecule e-cadherin (as opposed to n-cadherin, which is used by cells of the connective tissue).

Functions of epithelial cells include secretion, selective absorption, protection, transcellular transport and detection of sensation and they commonly as a result present extensive apical-basolateral polarity (e.g. different membrane proteins expressed) and specialisation.

This text uses material from Wikipedia licensed under CC BY-SA