News tagged with estrogen receptor
Scientists decode DNA to find breast tumor signatures that predict treatment response
Decoding the DNA of patients with advanced breast cancer has allowed scientists to identify distinct cancer "signatures" that could help predict which women are most likely to benefit from estrogen-lowering ...
Genetics
Jun 10, 2012 |
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BPA substitute could spell trouble: Experiments show bisphenol S also disrupts hormone activity
A few years ago, manufacturers of water bottles, food containers, and baby products had a big problem. A key ingredient of the plastics they used to make their merchandise, an organic compound called bisphenol A, had been ...
Health
Jan 22, 2013 |
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Researchers identify gene partly responsible for maternal care in mice
(Medical Xpress)—The medial preoptic area of the brain has been found over the years to be very closely involved with certain behaviors in mice, such as sexual proclivity, locomotion, aggression and the ...
Genetics
Sep 18, 2012 |
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BPA's real threat may be after it has metabolized
Bisphenol A or BPA is a synthetic chemical widely used in the making of plastic products ranging from bottles and food can linings to toys and water supply lines. When these plastics degrade, BPA is released ...
Health
Oct 04, 2012 |
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Three new genetic links to breast cancer identified
(Medical Xpress) -- An international team of researchers has identified three new genetic loci associated with an increased susceptibility to breast cancer. As described in their paper published in Nature Ge ...
Genetics
Jan 23, 2012 |
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Researchers identify new pathway, enhancing tamoxifen to tame aggressive breast cancer
Tamoxifen is a time-honored breast cancer drug used to treat millions of women with early-stage and less-aggressive disease, and now a University of Rochester Medical Center team has shown how to exploit tamoxifen's secondary ...
Cancer
Apr 23, 2013 |
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New breast cancer genetic alterations discovered
Breast cancer is not a single disease, but a collection of diseases with dozens of different mutations that crop up with varying frequency across different breast cancer subtypes. Deeper exploration of the genetic changes ...
Cancer
Jun 20, 2012 |
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Single protein promotes resistance to widely used anti-estrogen drugs
Researchers at Georgetown Lombardi Comprehensive Cancer Center have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women.
Cancer
Jul 02, 2012 |
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Higher estrogen production in the breast could confer greater cancer risk than thought
Could some women who naturally produce excess aromatase in their breasts have an increased risk of developing breast cancer? Results of a new animal study suggests that may be the case, say researchers at Georgetown Lombardi ...
Cancer
Aug 12, 2011 |
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Cold winters freezing out breast cancer treatment
For women diagnosed with a form of breast cancer known as estrogen receptor positive (ER+) breast cancer, tamoxifen is an essential drug used in the treatment and prevention of recurring breast cancer. Currently, tamoxifen ...
Cancer
Apr 18, 2013 |
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Polymorphism in estrogen receptor alpha linked to back pain
(HealthDay)—For women with degenerative spondylolisthesis (DS), polymorphisms in the estrogen receptor α (ERα) are associated with back pain intensity, according to a study published in the April issue ...
Diseases, Conditions, Syndromes
Apr 11, 2013 |
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Paragazole excels in preclinical models of triple-negative breast cancer
Breast cancers that lack estrogen receptors are more difficult to treat than ER+ cancers. Research presented at the AACR Annual Meeting 2013 demonstrates an investigational drug, Paragazole, that makes triple-negative ...
Cancer
Apr 08, 2013 |
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Breast cancer recurrence defined by hormone receptor status
Human epidermal growth factor (HER2) positive breast cancers are often treated with the same therapy regardless of hormone receptor status. New research published in BioMed Central's open access journal Breast Cancer Research shows ...
Cancer
Oct 01, 2012 |
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Estrogen may improve pathway-selective insulin resistance
(HealthDay)—Estrogen treatment at the time of surgical menopause may reverse aspects of pathway-selective insulin resistance in the liver associated with a high-fat diet (HFD) in mice by promoting insulin ...
Diabetes
Feb 14, 2013 |
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Reducing the side effects of treatment for prostate cancer
New research published in BioMed Central's open access journal BMC Medicine reassessing clinical data from trials, which investigate ways of treating side effects of therapy for prostate cancer, finds that tamoxifen, an ant ...
Cancer
Aug 27, 2012 |
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Estrogen receptor
Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.
The main function of the estrogen receptor is as a DNA binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding.
For more information about Estrogen receptor, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
