Estrogen is known to play an important role in the protection of women's hearts, but once women are postmenopausal and estrogen levels drop, they are at an increased risk of a number of diseases and conditions, including ...
Mar 10, 2023
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Bisphenol S (BPS), a substitute for the chemical bisphenol A (BPA) in the plastic industry, shows the potential for increasing the aggressiveness of breast cancer through its behavior as an endocrine-disrupting chemical, ...
Apr 2, 2017
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A personalized prognosis for patients diagnosed with triple-negative breast cancer was the goal of a new study by Katherine Varley, Ph.D., researcher at Huntsman Cancer Institute (HCI) and assistant professor of oncological ...
Jun 13, 2019
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One member of a larger family of oxygen sensing enzymes could offer a viable target for triple negative breast cancer (TNBC), UTSW researchers report in a new study. The findings, published online this week in Cancer Discovery, ...
Jul 22, 2020
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Researchers at the University of Cincinnati (UC) have identified a key protein as the first dual-function co-regulator of an estrogen receptor that plays a crucial role in cancer development, opening the way to improved therapeutic ...
Aug 30, 2013
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Recently published research shows that coffee drinkers enjoy not only the taste of their coffee but also a reduced risk of cancer with their cuppa. More detailed research published today in BioMed Central's open access journal ...
May 11, 2011
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The menopause transition is associated with several health issues. The incidence of both sleep apnea and joint pain, for example, are higher in postmenopausal women. A new study aimed to investigate the association between ...
Mar 2, 2022
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A new approach to treating breast cancer kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ...
Jul 21, 2021
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A compound, developed by a team including scientists from The University of Texas Health Science Center at San Antonio, kills a range of hard-to-treat cancer types in petri dishes and animal models by targeting a previously ...
Jun 2, 2022
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Past research findings suggest that women who are addicted to cocaine are more sensitive to cocaine-related stimuli that make them crave the drug and relapse into addiction. However, other studies suggest that steroid hormones ...
Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.
The main function of the estrogen receptor is as a DNA binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding.
This text uses material from Wikipedia, licensed under CC BY-SA
