Weight loss surgery not only shrinks waists but also affects genes
Gastric bypass surgery can drastically reduce the body weight of obese individuals in a short timeframe. For reasons that are not entirely clear, the surgery also leads to early remission of type 2 diabetes in the vast majority ...
Medical research
Apr 11, 2013 |
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Genetic master controls expose cancers' Achilles' heel
In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, Whitehead Institute scientists have discovered a set of powerful gene regulators dubbed "super-enhancers" that control cell state ...
Cancer
Apr 11, 2013 |
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Researchers identify novel approach to study COPD and treatment efficacy
(Medical Xpress)—Researchers from Boston University School of Medicine (BUSM) have pinpointed a genetic signature for chronic obstructive pulmonary disease (COPD) from airway cells harvested utilizing a minimally invasive ...
Diseases, Conditions, Syndromes
Apr 11, 2013 |
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Genes reveal which patients will benefit from scleroderma drug
Systemic sclerosis, also known as scleroderma, is a rare autoimmune connective tissue disorder that's difficult to treat. However, thanks to new research at Northwestern University Feinberg School of Medicine and Dartmouth's ...
Diseases, Conditions, Syndromes
Apr 10, 2013 |
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K9 osteosarcoma samples identify drivers of metastasis in pediatric bone cancer
Human osteosarcoma samples are hard to come by, making the disease difficult to study. However, K9 bone cancer is genetically indistinguishable from the human form of the disease, and over 10,000 canine patients develop the ...
Cancer
Apr 09, 2013 |
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Little molecule makes big difference in bladder cancer metastasis
In order to kill, bladder cancer must metastasize, most commonly to the lung – what are the differences between bladder cancers that do and do not make this deadly transition? Research presented by the Director of the University ...
Cancer
Apr 09, 2013 |
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New target plus new drug equals death of melanoma cells
Collaborative research presented by the University of Colorado Cancer Center, the University of North Carolina at Chapel Hill, Harvard Medical School and the University of Pittsburgh, at the American Association for Cancer ...
Cancer
Apr 09, 2013 |
5 / 5 (1) |
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Study finds key to calling back-up help when tumor-fighter p53 goes down
Tumor suppression, the family business of the sibling genes p53, p63 and p73, is undermined from within by the split personalities of p63 and p73, which each produce protein forms that not only block the work of the other ...
Cancer
Apr 08, 2013 |
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New HIV findings reveal genetic double-edged sword
A major international research study involving Murdoch University has found that individuals born with high numbers of a receptor known as HLA-C on their cells can naturally inhibit HIV.
HIV & AIDS
Apr 05, 2013 |
3 / 5 (2) |
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Shutting down DNA construction: How senescence halts growth of potential cancers
Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides—the building blocks ...
Cancer
Apr 04, 2013 |
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Comparing mouse and human immune systems: Few differences charted in map to translate mouse findings to humans
(Medical Xpress)—It is a familiar note struck when authors conclude their reports on experiments conducted in mouse models: They suggest caution when translating their findings from mouse to human. A variation ...
Medical research
Apr 02, 2013 |
4 / 5 (1) |
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New multiple myeloma treatment guidelines personalize therapy for patients
Researchers at Mayo Clinic Cancer Center have developed new guidelines to treat recently diagnosed multiple myeloma patients who are not participating in clinical trials. The guidelines give physicians practical, easy to ...
Cancer
Apr 01, 2013 |
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Innovative method to treat Alzheimer's in mice
Researchers from the RIKEN Brain Science Institute report that they successfully used a virus vector to restore the expression of a brain protein and improve cognitive functions, in a mouse model of Alzheimer's ...
Alzheimer's disease & dementia
Apr 01, 2013 |
5 / 5 (1) |
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Mechanism of mutant histone protein in childhood brain cancer revealed
(Medical Xpress)—Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. ...
Cancer
Apr 01, 2013 |
5 / 5 (1) |
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New vaccine-design approach targets HIV and other fast-mutating viruses
A team led by scientists from The Scripps Research Institute (TSRI) and the International AIDS Vaccine Initiative (IAVI) has unveiled a new technique for vaccine design that could be particularly useful against ...
HIV & AIDS
Mar 28, 2013 |
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