Medical research
New mechanism controlling proper organization of the muscle contractile units indentified
Muscle-specific protein cofilin-2 controls the length of actin filaments in muscle cells.
Nov 7, 2014
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News tagged with filaments
Immunology
Bacteria and immune cells forge a productive partnership
To prevent infection, the intestinal wall relies on the support of its own 'home-grown' army of commensal bacteria. These gut microbiota collaborate with and are in turn regulated by their host's immune system via a variety ...
Nov 7, 2014
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Oncology & Cancer
p53 cuts off invading cancer cells
The tumor suppressor p53 does all it can to prevent oncogenes from transforming normal cells into tumor cells by killing defective cells or causing them to become inactive. Sometimes oncogenes manage to initiate tumor development ...
Mar 24, 2014
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Medical research
Protein that protects nucleus also regulates stem cell differentiation
The human body has hundreds of different cell types, all with the same basic DNA, and all of which can ultimately be traced back to identical stem cells. Despite this fundamental similarity, a bone cell has little in common ...
Aug 29, 2013
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Neuroscience
Splice this: End-to-end annealing demonstrated in neuronal neurofilaments
While popularly publicized neuroscience research focuses on structural and functional connectomes, timing patterns of axonal spikes, neural plasticity, and other areas of inquiry, the intraneuronal environment also receives ...
Medical research
Low levels of toxic proteins linked to brain diseases, study suggests
Neurodegenerative diseases such as Alzheimer's could be better understood thanks to insight into proteins linked to such conditions, a study suggests.
Jul 2, 2013
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Neuroscience
Alzheimer's disease mouse models point to a potential therapeutic approach
Building on research published eight years ago in the journal Chemistry and Biology, Kenneth S. Kosik, Harriman Professor in Neuroscience and co-director of the Neuroscience Research Institute (NRI) at UC Santa Barbara, and ...
Jun 26, 2013
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Medical research
Rare, lethal childhood disease tracked to protein
A team of international researchers led by Northwestern Medicine scientists has identified how a defective protein plays a central role in a rare, lethal childhood disease known as Giant Axonal Neuropathy, or GAN. The finding ...
Apr 29, 2013
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Medical research
Cholesterol increases risk of Alzheimer's and heart disease
Researchers at the Linda Crnic Institute for Down Syndrome and the University of Colorado School of Medicine have found that a single mechanism may underlie the damaging effect of cholesterol on the brain and on blood vessels.
Apr 15, 2013
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Medical research
Rare, lethal childhood disease tracked to failure to degrade nerve cells' filaments
For the first time, a defective protein that plays a specific role in degrading intermediate filaments (IF), one of three classes of filaments that form the structure of nerve cells, has been discovered by an international ...
Dec 17, 2012
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