A small protein called SUMO might prevent the protein aggregations that typify Parkinson's disease (PD), according to a new study in the July 11, 2011, issue of The Journal of Cell Biology.
Jul 11, 2011
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Researchers at the MRC Laboratory of Molecular Biology (LMB) have revealed the atomic structures of the abnormal tau filaments associated with chronic traumatic encephalopathy (CTE), a head injury-associated neurodegenerative ...
Mar 21, 2019
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Artificial muscles and self-propelled goo may be the stuff of Hollywood fiction, but for UC Santa Barbara scientists Omar Saleh and Deborah Fygenson, the reality of it is not that far away. By blending their areas of expertise, ...
Oct 23, 2012
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On Dec. 14, 2014, after many months of not getting expected results, biochemist Jim Spudich got into bed, read a chunk of a novel, fell asleep and had a dream that would change the focus of his entire field in thinking about ...
Mar 21, 2019
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More than 90% of people with Down syndrome, the most common chromosomal disorder in humans and the most frequent genetic cause of intellectual disability, are diagnosed with Alzheimer's disease by ages 55–60.
Mar 29, 2024
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Astrocytes are cells that have many functions in the central nervous system, such as the control of neuronal synapses, blood flow, or the brain's response to neurotrauma or stroke.
Aug 24, 2012
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A team of researchers with the MRC Laboratory of Molecular Biology in the U.K. and Indiana University School of Medicine in the U.S. has determined the structure of tau filaments in patients with Pick's disease. In their ...
Abnormal accumulation of misfolded tau protein in filaments characterizes numerous neurodegenerative diseases—collectively called tauopathies for this very reason. A long-standing collaboration between Michel Goedert's ...
Sep 30, 2021
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Indiana University School of Medicine researchers are making new discoveries about the pathological changes in people who have inherited Alzheimer's disease versus developing the disease sporadically. These findings could ...
Jan 20, 2022
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New research from scientists at the Wu Tsai Neurosciences Institute at Stanford University has identified a key driver of myelination, the formation of protective fatty sheaths around nerve fibers.
Mar 25, 2024
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