New safety data from a study of patients with advanced Parkinson's disease five years after gene transfer-mediated delivery of the neuroprotective factor neurturin directly to patients' brains reveal no serious adverse events ...
Jul 27, 2016
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The long-term safety of gene transfer to treat neovascular age-related macular degeneration (NVAMD), and the production of two therapeutic proteins encoded by those genes for at least 2.5 years in the eyes of patients with ...
Oct 20, 2016
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A new gene therapy approach designed to replace the enzyme that is deficient in patients with the inherited neurodegenerative disorders Tay-Sachs and Sandhoff diseases successfully delivered the therapeutic gene to the brains ...
Jul 28, 2016
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Japanese researchers developed a gene transfer technique that can "eliminate" a specific neural circuit in non-human primates for the first time in the world.
Jun 26, 2012
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Use of intracoronary gene transfer among heart failure patients resulted in increased left ventricular function beyond standard heart failure therapy, according to a study published online by JAMA Cardiology.
Mar 30, 2016
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The bacterium Streptococcus pneumoniae – which can cause pneumonia, meningitis, bacteremia and sepsis – likes to share its antibiotic-defeating weaponry with its neighbors. Individual cells can pass resistance genes to ...
Oct 24, 2012
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(Medical Xpress)—Researchers at Iowa State University have identified a genetic process by which some Escherichia coli bacteria adapt to the human kidney, a step that could lead to new treatments to stop urinary tract infections.
Aug 23, 2013
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Some strains of Streptococcus pneumoniae—a disease-causing bacterium—possess a cell-to-cell signaling system that may influence gene expression and virulence in co-colonizing strains, according to a study published in ...
May 18, 2017
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Gene transfer therapy aimed at correcting an enzyme abnormality involved in myocardial contraction and relaxation did not improve outcomes in heart failure patients with reduced ejection fraction, results of the CUPID 2 study ...
Sep 1, 2015
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(HealthDay)—For men with severe hemophilia A, high-dose factor VIII gene transfer is associated with sustained normalization of factor VIII activity levels, according to a study published online Dec. 9 in the New England ...
Dec 11, 2017
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