In the past decade, knowledge of how lifestyle affects our genes, a research field called epigenetics, has grown exponentially. Researchers at Lund University have summarised the state of scientific knowledge within epigenetics ...
Apr 24, 2019
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Cardiovascular diseases (CVD) lead to atherosclerosis and heart failure and are prevalent age-related illnesses in humans. In a new study, published in the renowned journal JCI, scientists from Roland Foisner's group at the ...
Jan 8, 2019
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Disorders of the autistic spectrum have been associated with hundreds of genetic variations, which have helped in identifying disturbed intracellular signalling pathways and molecular mechanisms typical to autism.
Dec 4, 2018
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About three per cent of the world's population is affected by valvular heart diseases. It is also the most common cause of heart surgery, as no drug-based treatment is available. Recent research has shed light on the molecular ...
Nov 20, 2018
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Targeted treatments have revolutionized care for lung cancer patients whose tumors harbor ALK or ROS1 alterations. Basically, cancers may use these genetic changes to drive their growth, but also become dependent on the action ...
Apr 11, 2018
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How can defective gene activity leading to cancerbe avoided? Researchers at the University of Zurich have now identified a mechanism by which cells pass on the regulation of genetic information through epigenetic modifications. ...
Oct 30, 2017
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Early-stage colon cancer patients could benefit in the future from specific genetic tests that forecast their prognosis and help them make the right decision regarding chemotherapy. Two of the biomarkers involved are the ...
Jul 26, 2017
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The genetic mutations underlying treatment resistance in non-small cell lung cancer (NSCLC) are more complex and dynamic than previously thought. Analysis of 355 biopsied tumors from patients who acquired resistance to EGFR ...
Mar 16, 2017
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A University of Colorado Cancer Center study presented at the American Association for Cancer Research Annual Meeting 2016 pinpoints ways that cancer cells evolve to resist the drug LOXO-101, a kinase inhibitor of the TRK-fusion ...
Apr 18, 2016
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There is a well-described association between UV radiation exposure from the sun and the development of melanoma. The development of melanoma independent of sun exposure has only recently been described in mice.
Apr 6, 2016
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